Association of Hyperhomocysteinemia and Coronary Heart Disease in South Indian Population

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Authors

  • Department of Cardiology and Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507 ,IN
  • Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507 ,IN
  • Department of Cardiology and Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507 ,IN
  • Department of Cardiology and Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507 ,IN
  • Department of Cardiology and Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507 ,IN

Abstract

Mccully first reported association of elevated levels of homocysteine with vascular disease. It was later confirmed by Wilken and Wilken in a case-control study. Development of aggressive, premature vascular disease with homocystinuria led to the hypothesis that mild to moderate elevations in plasma homocysteine might contribute to the development and progression of atherosclerosis in adults. Reduction of cardiovascular risk in homocystinuric patients with dietary methionine restriction and B vitamin supplementation suggested a causal role of higher levels of homocysteine in vascular pathology of homocystinuria.

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Published

2006-04-01

How to Cite

Rajasekhar, D., Srinivasa Rao, P. V. L. N., Latheef, S. A. A., Subramanyam, G., & Saibaba, K. S. S. (2006). Association of Hyperhomocysteinemia and Coronary Heart Disease in South Indian Population. The Indian Journal of Nutrition and Dietetics, 43(4), 146–152. Retrieved from http://informaticsjournals.com/index.php/ijnd/article/view/6350

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Original Articles