Adrenocorticotropin Secretion from Peripheral Blood Mononuclear Cells in Cyclic and Pregnant Animals

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Authors

  • N. Parvizi
     Department of Functional Genomics and Bioregulation, institute of Animal Science, FAL Mariensee, 31535 Neustadt ,DE
  • J. Phogat
     Department of Functional Genomics and Bioregulation, Institute of Animal Science, FAL Mariensee, 31535 Neustadt ,DE
  • B. Glatz-Vinke
     Department of Functional Genomics and Bioregulation, institute of Animal Science, FAL Mariensee, 31535 Neustadt ,DE
  • D. V. Dixit
     Department of Functional Genomics and Bioregulation, institute of Animal Science, FAL Mariensee, 31535 Neustadt ,DE

Keywords:

ACTH, Lymphocytes, Pripheral Blood Mononuclear Cells, Estrous Cycle, Pregnancy.

Abstract

A growing body of evidence suggests that a number of classical pituitary hormones are also produced and secreted from immune cells. The cross-talk between endocrine and the immune system is heightened during disease, stress and pregnancy. We studied the adrenocorticotropin (ACTH) secretion from peripheral blood mononuclear cells (PBMC) harvested from cyclic and pregnant animals. Our results indicate a significantly high secretion of ACTH from PBMCs in all stages of pregnancy compared to that in cyclic animals. This implies a new role for ACTH secreted from PBMCs in fetomaternal immune interactions.

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Published

2004-12-01

How to Cite

Parvizi, N., Phogat, J., Glatz-Vinke, B., & Dixit, D. V. (2004). Adrenocorticotropin Secretion from Peripheral Blood Mononuclear Cells in Cyclic and Pregnant Animals. Journal of Endocrinology and Reproduction, 8(1&2), 95–100. Retrieved from http://informaticsjournals.com/index.php/jer/article/view/4530

Issue

Volume 8, Issue 1&2, June-December 2004

Section

Review