Anti-Inflammatory Activity of Rubia cordifolia Roots

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  • ,IN
  • ,IN
  • ,IN

DOI:

https://doi.org/10.18311/jnr/2001/17

Keywords:

Rubia cordifolia, Antiinflammatory Activity.
Therapeutic Drug Monitoring

Abstract

Objective: To study the anti-inflammatory, analgesic, antipyretic and gastrolesive properties of petroleum ether extract of Rubia cordifolia roots. Materials and methods: Bioassay guided separation of petroleum ether extract was carried out to obtain a compound possessing anti-inflammatory activity. An active triterpene responsible for the anti-inflammatory activity was separated. The compound exhibited anti-inflammatory activity in the carrageenan-induced edema, cotton pellet granuloma and adjuvant-induced arthritis. The analgesic activity was studied using acetic acid induced writhing and radiant heat analgesiometer and antipyretic activity was assessed in yeast-induced hyperpyrexia in rats. The ulcerogenic potential was studied using pyloric ligated rats. Results: The compound possesses anti inflammatory, analgesic and antipyretic activity and strong gastrolesive properties. Conclusion: The study justifies the use of Rubia cordifolia in the treatment of inflammation, pain and fever.

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Published

2001-07-01

How to Cite

Kasture, S. B., Kasture, V. S., & Chopde, C. T. (2001). Anti-Inflammatory Activity of <I>Rubia cordifolia</I> Roots. Journal of Natural Remedies, 1(2), 111–115. https://doi.org/10.18311/jnr/2001/17

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