Analgesic and Anti-Inflammatory Activity of Couroupita guianensis Aubl.

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  • ,IN
  • ,IN
  • ,IN
  • ,IN

DOI:

https://doi.org/10.18311/jnr/2004/382

Keywords:

Couroupita guianensis, Analgesic Activity, Anti-inflammatory Activity, Paracetamol, Indomethacin.
Therapeutic Drug Monitoring

Abstract

Objective: To study analgesic and anti-inflammatory activity of various extracts of flowers and bark of Couroupita guianensis Aubl. Materials and methods: Analgesic activity was evaluated using tail flick method and anti-inflammatory activity was screened by measuring the reduction in carrageenan induced hind paw oedema. The potency of various extracts of flower and bark were compared with (i) paracetamol (200 mg/kg) for analgesic and (ii) indomethacin (10 mg/kg) for anti-inflammatory activities. Results: All the extracts of C. guianensis showed analgesic and anti-inflammatory activity. The peak analgesic effect of flower was seen after 1 h while bark extracts showed peak effect after 2 h. Maximum reduction in inflammation by the extracts was observed after 3 h. Conclusion: C. guianensis is almost equipotent to paracetamol in its analgesic activity and to indomethacin in its anti-inflammatory activity. So it can be recommended for further studies.

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Published

2004-01-01

How to Cite

Geetha, M., Saluja, A. K., Shankar, M. B., & Mehta, R. S. (2004). Analgesic and Anti-Inflammatory Activity of <I>Couroupita guianensis</I> Aubl. Journal of Natural Remedies, 4(1), 52–55. https://doi.org/10.18311/jnr/2004/382

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