In vitro Antioxidant and Antilipidperoxidative Potential of Calocybe indica


Affiliations

  • Bannari Amman Institute of Technology, Department of Biotechnology, Sathy, India
  • Karunya Institute of Technology, Department of Biotechnology, Coimbatore, India
  • Dr. N.G.P. Arts and Science College, Coimbatore, India
  • Kovai Medical Centre and Research Institute, Institute of Laboratory Medicines, Coimbatore, India

Abstract

The ethanolic extract of Calocybe indica was studied for its free radical scavenging property on different in vitro models like 1, 1-diphenyl-picryl hydrazyl (DPPH) Assay, Ferric Reducing Antioxidant Power (FRAP) assay and in vitro antilipidperoxidative assay using goat liver homogenate and RBC Ghost model. The in vitro Lipid peroxidation (LPO) was inhibited to a good extent by the Calocybe indica ethanolic extract and the extent of inhibition being higher in the RBC membrane model than the liver homogenate model. The mushroom extract showed good dose-dependent free radical scavenging property in both the models.

Keywords

Free Radical Scavenging, Calocybe indica, Antioxidant.

Subject Discipline

Pharmacy and Pharmacology

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