Phytochemical Screening and Blood Glucose Level Lowering Effect of Bergenia ligulata Root Extracts


Affiliations

  • S.G.R.R.I.T.S., Division of Pharmaceutical Sciences, Dehradun, Uttarakhand, India
  • S.G.R.R.I.T.S., Department of Chemistry, Dehradun, Uttarakhand, India
  • Kumaun University, Department of Pharmacy, Nanital, Uttarakhand, India

Abstract

The present study was carried out to evaluate the blood sugar level lowering effect of different extract of Bergenia ligulata root i.e. Pet. ether, Solvent ether, Chloroform, Acetone and Ethanol extracts in alloxan induced diabetic rats. The duration of study was 15 days. Blood sugar level lowering activity was evaluated by measuring the Blood sugar level and lipid profile (Total Cholesterol, Total Glyceride, High Density Lipoprotein, Low Density Lipoprotein, and Very Low Density Lipoprotein). The acetone extract has shown significant effect on blood sugar level at a dose of (500 mg/kg,b.w, p.o/day). The study results suggested the Bergenia ligulata roots possess' significant activity. The different extract of the root of Bergenia ligulata were subjected to preliminary phytochemical screening and reveals the presence of Alkaloids, Glycosides, Tannins, Flavonoids and Sterols.

Keywords

Bergenia ligulata Root, Blood Sugar, Alloxan and Glucometer.

Subject Discipline

Pharmacy and Pharmacology

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