An Institutional Study for Determining the Correlation of Oral Submucous Fibrosis with Serum Haemoglobin Level: A Retrospective Analysis of 100 Cases
Materials and methods: In this institutional study, 100 clinically diagnosed and histopathologically confirmed OSF patients were retrieved, of which 68 patients were included in the study along with 30 healthy controls. Serum haemoglobin levels were retrieved retrospectively from the haematological records.
Results: The study showed no significant correlation between OSF and serum haemoglobin. Serum haemoglobin in the study group and the control group did not show any significant difference.
Conclusion: There is no significant correlation between the serum haemoglobin level with OSF and also with control groups. Further large-scale prospective studies with different stages of OSF are indicated to find a correlation between the level of serum haemoglobin and OSF in this part of the country.
Warnakulasuriya S, Johnson NW, Van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36: 575–580.
Hegde K, Nair P, Gharote HP, Agarwal K, Bhat GR, Rajaram DK. Role of hemoglobin and serum iron in oral submucous fibrosis: a clinical study. Sci World J. 2012;2012:.
Rajendran R, Vijayakumar T, Vasudevan DM. An alternative pathogenetic pathway for oral submucous fibrosis (OSMF). Med Hypotheses. 1989;30:35–37.
Khanna S. Immunological and biochemical markers in oral carcinogenesis: the public health perspective. Int J Environ Res Public Health. 2008;5:418–422.
Kumar KK, Saraswathi TR, Ranganathan K, Uma Devi M, Joshua E. Oral submucous fibrosis: a clinicohistopathological study in Chennai. Indian J Dent Res. 2007;18:108–111.
Pandya S, Chaudhary AK, Singh M, Mehrotra R. Correlation of histopathologic diagnosis with habits and clinical findings in Oral Submucous Fibrosis. Head Neck Oncol. 2009;1:10.
Seedat HA, Van Wyk CW. Betel-nut chewing and submucous fibrosis in Durban. SAMJ. 1988;74:568–571.
Rajendran R. Oral submucous fibrosis: etiology, pathogenesis, and future research. Bull World Health Organ. 1994;72:985–996.
Clark SF. Iron deficiency anemia: diagnosis and management. Curr Opin Gastroenterol. 2009;25:122–128.
Rajendran R, Sivapathasundharam B. Shafer's Textbook of Oral Pathology. 6th ed. Elsevier India; 2009:86–100.
Kakar PK, Puri RK, Venkatachalam VP. Oral submucous fibrosis—treatment with hyalase. J Laryngol Otol. 1985;99: 57–59.
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