Bioinformatics and Experimental Databases as Significant Research Paraphernalia in Oral Cancer - A Narrative Review

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Authors

  • Deepti Sharma
     Department of Oral and Maxillofacial Pathology, Christian Dental College and Hospital, Ludhiana -141008, Punjab ,IN
  • George Koshy
     Department of Oral and Maxillofacial Pathology, Christian Dental College and Hospital, Ludhiana -141008, Punjab ,IN
  • Vishal Kumar Sharma
     Department of Orthodontics, Desh Bhagat Dental College, Mandi Gobindgarh - 147301, Punjab ,IN

DOI:

https://doi.org/10.18311/jpfa/2023/32255

Keywords:

Bioinformatics, Data Mining, Genome, Insilco, Microarrays, Next Generation Sequencing, Oral Cancer

Abstract

Among head and neck squamous cell carcinomas the incidence of Oral Squamous Cell Carcinoma (OSCC) is highest (80%). Bioinformatics provides a wide-ranging outlook to understand the significant genes, proteins, pathways, and molecular mechanisms fundamental to oral carcinogenesis. It is a promising branch in the field of biomedical research with emerging popularity in the field of dental research too, targeting immune-mediated, developmental, genetic, and malignant diseases. High-throughput experimental technologies have created large and complex genomic data, which has revolutionized genomic research. Advanced technologies including microarray, next-generation sequencing, and bioinformatics together play a decisive role in unraveling the molecular mechanism in the process of Head and Neck cancer. This article is an attempt to give an overview of the significant role of bioinformatics in the field of genomic research.

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Published

2023-09-11

How to Cite

Sharma, D., Koshy, G., & Sharma, V. K. (2023). Bioinformatics and Experimental Databases as Significant Research Paraphernalia in Oral Cancer - A Narrative Review. Journal of Pierre Fauchard Academy (India Section), 37(1-2), 01–08. https://doi.org/10.18311/jpfa/2023/32255

Issue

Volume 37, Issue 1-2, January-June 2023

Section

Review Article

License

All the articles published in JPFA are distributed under a creative commons license. The journal allows the author(s) to hold the copyright of their work (all usages allowed except for commercial purpose).

 

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