Prediction of an Infarct Related Artery on Electrocardiogram and its Correlation with Coronary Angiography in an Acute Myocardial Infarction

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Authors

  • Former PG Resident, Department of Medicine, Dr. Vasantrao Pawar Medical College Hospital & Research Centre, Nashik – 422203 ,IN
  • Professor, Department of Medicine, Dr. Vasantrao Pawar Medical College Hospital & Research Centre, Nashik – 422203 ,IN

Keywords:

Acute Myocardial Infarction, Coronary Angiography, Electrocardiography

Abstract

Aim: To Predict an infarct related artery on Electrocardiogram and its correlation with Coronary angiography in an Acute myocardial Infarction. Materials and Methods: The study was carried out as a prospective observational study of 70 patients at medical college & tertiary health care Centre, over a period of two years that included cases of patients diagnosed to have acute myocardial infarction on ECG for the first time & have also undergone coronary angiography. Results: Study showed most common age group amongst study population was 51 to 60 yrs (42.9%) followed by 61 to 70 yrs (37.1%). LAD (71%) was the most common coronary artery amongst study population followed by RCA (25%) and LCX (4%). Most of the study population had ECG findings like ST depression III + aVF ≥ 2.5 (36%) and ST segment in III and aVF isoelectric or elevated (36%) followed by ST depression in III + aVF ≤ 2.5 and ≥ 0.5 (28%) in LAD occlusion. In the present study, most of the study population had ECG findings like ST↑LIII > ST↑ LII > 1 (94.12%), ST↓LI, aVL (82.35%) and ST↑V4R > 1 mm (70.59%) in RCA occlusion. In the present study, most of the study population had ECG findings like ST ↑ LII > LIII (100%) and Isoelectric or ST ↑ I,aVL (66.7%) in LCX occlusion. Conclusion: ECG criteria have excellent sensitivity and specificity in predicting the culprit artery Anterior ST elevation identified all patients with LAD as the culprit artery with 100 % accuracy in our study population. In patients with inferior ST elevation, relative ratio of ST elevation in lead II and lead III, correctly identified the culprit artery as RCA or LCx with 100 % accuracy. (ST elevation in lead II > III predicts LCx occlusion and the reverse predicts RCA occlusion.

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2021-01-01

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References

Srinath Reddy K, Shah B, Varghese C, Ramadoss A. Responding to the threat of chronic diseases in India. Lancet. 2005; 366: 1744–1749. https://doi.org/10.1016/ S0140-6736(05)67343-6

Joshi P, Islam S, Pais P, Reddy S, Dorairaj P, Kazmi K, Pandey MR, Haque S, Mendis S, Rangarajan S, Yusuf S. Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. JAMA. 2007; 297: 286–294. https://doi.org/10.1001/jama.297.3.286

Xavier D, Pais P, Devereaux PJ, Xie C, Prabhakaran D, Reddy KS, Gupta R, Joshi P, Kerkar P, Thanikachalam S, Haridas KK, Jaison TM, Naik S, Maity AK, Yusuf S; CREATE registry investigators. Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data. Lancet. 2008; 371: 1435–1442. https://doi.org/10.1016/S0140-6736(08)60623-6

Harikrishnan S, Leeder S, Huffman M, Jeemon P, Prabhakaran D. A Race against Time: The Challenge of Cardiovascular Disease in Developing Economies. 2nd ed. New Delhi, India: New Delhi Centre for Chronic Disease Control; 2014.

Global Atlas on Cardiovascular Disease Prevention and Control. Geneva, Switzerland: World Health Organization; 2011.

Birnbaum, Y, and B Drew. “The Electrocardiogram in ST Elevation Acute Myocardial Infarction: Correlation with Coronary Anatomy and Prognosis.â€Postgraduate Medical Journal. 79.935 (2003): 490–504. https://doi.org/10.1136/ pmj.79.935.490

Tragardh E, Claesson M, Wagner GS, Zhou S, Pahlm O. Detection of acute myocardial infarction using the 12-lead ECG plus inverted leads versus the 16-lead ECG (with additional posterior and right-side chest electrodes). Clin Physiol Funct Imaging. 2007; 27(6): 368–74. https://doi. org/10.1111/j.1475-097X.2007.00761.x

Scharovsky S. Electrocardiography of acute myocardial ischaemic syndromes. London, UK: Martin Dunitz Ltd; 1999.

CS, Thejanandhan & Rajasekhar, Durgaprasad & Vanajakshamma, Velam. (2013). Electrocardiographic localization of infarct related coronary artery in acute ST- elevation myocardial infarction. Journal of Clinical and Scientific Research. 2: 151-60. 10.15380/2277-5706.JCSR.12.084.

Celik T, Yuksel UC, Iyisoy A, Kilic S, Kardesoglu E, Bugan B, et al.. The impact of preinfarction angina on electrocardiographic ischemic grades in patients with acute myocardial infarction treated with primary percutaneous coronary intervention. Ann Noninvasive Electrocardiol. 2008; 13(3): 278–86. https://doi.org/10.1111/j.1542-474X.2008.00232.x

Radhakrishnan Nair D Luke Glancy. ECG discrimination between right and left circumflex coronary artery occlusion in patients with acute IW MI. Chest July 2002. 122; 134–139. https://doi.org/10.1378/chest.122.1.134

D. Hambire et al., Prediction of an Infarct Related Artery on Electrocardiogram and its Correlation with Coronary Angiography in an Anterior Wall Acute Myocardial Infarction. IJSR, 2015; 4:1:371–74.

Krahn AD, Klein GJ, Yee R, Takle-Newhouse T, Norris C. Takle-Newhouse T. Use of an extended monitoring strategy in patients with problematic syncope. Circulation 1999; 99(3): 406–410. https://doi.org/10.1161/01.CIR.99.3.406

Rusher RF. Cardiac compensation, hypertrophy, myopathy and congestive heart failure. In: Cardiovascular dynamics. 3rd ed. Philadelphia: WB Saunders; 1976; 532–565.

Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52countries (the INTERHEART study):case-control study. Lancet 2004; 364: 937–952. https://doi.org/10.1016/S0140-6736(04)17018-9

Alappatt NJ, Sailesh KS, Mukkadan JK. Clinical profile of acute coronary syndrome in young adults. J Med Sci Health 2016; 2(1): 5–10. https://doi.org/10.46347/JMSH.2016. v02i01.002

Sadia Huma, Rabia Tariq, Dr Fatima Amin1, Dr. Khawaja Tahir Mahmood, Modifiable and Non-modifiable predisposing Risk Factors of Myocardial Infarction -A Review, Sadia Huma et al. J. Pharm. Sci. & Res. 4(1), 2012,1649– 1653.

Deborah A. Chyun, Lawrence H. Young, Diabetes Mellitus and Cardiovascular Disease, Nurs Clin N Am 41, 2006: 681–695. https://doi.org/10.1016/j.cnur.2006.07.007

Wander GS, Khurana SB, Gulati R, Sachar RK, Gupta RK, Khurana S, et al. Epidemiology of coronary heart disease in a rural Punjab population – prevalence and correlation with various risk factors. Indian Heart J 1994; 46: 319–23.

Luis Martínez-Dolz et al., Usefulness of the Electrocardiogram in Predicting the Occlusion Site in Acute Anterior Myocardial Infarction with Isolated Disease of the Left Anterior Descending Coronary Artery, Rev Esp Cardiol. 2002; 55: 1036–41

Arbane M, Goy JJ. Prediction of the site of total occlusion in the left anterior descending coronary artery using admission electrocardiogram in anterior wall acute myocardial infarction. Am J Cardiol 2000; 85: 487–91. https:// doi.org/10.1016/S0002-9149(99)00777-8

Tamura A, Kataoka H, Mikuriya Y, Nasu M. Inferior ST-segment depression as a useful marker for identifying proximal left anterior descending coronary artery occlusion during acute anterior myocardial infarction. Eur Heart J. 1995; 16: 1795–9. https://doi.org/10.1093/oxfordjournals. eurheartj.a060830

Birnbaum Y, Solodky A, Herz I, Kusniec J, Rechavia E, Sulkes J, et al. Implication of inferior ST-segment depression in anterior acute myocardial infarction: electrocardiographic and angiographic correlation. Am Heart J. 1994; 127: 1467– 73. https://doi.org/10.1016/0002-8703(94)90372-7

Lew AS, Hod H, Cercek B, Shah PK, Ganz W. Inferior ST segment changes during acute anterior myocardial infarction: a marker of the presence or absence of concomitant inferior wall ischemia. J Am Coll Cardiol. 1987; 10: 519– 26. https://doi.org/10.1016/S0735-1097(87)80193-6

Haraphongse M, Tanomsup S, Jugdutt BI. Inferior ST segment depression during acute anterior myocardial infarction: clinical and angiographic correlations. J Am Coll Cardiol. 1984; 4: 467–76. https://doi.org/10.1016/ S0735-1097(84)80089-3

Willens JL, Willems RJ, Willems GM, Arnold AE. R, Van de Werf F, Verstraete M. Significance of initial ST segment elevation and depression for the management of thrombolytic therapy in acute myocardial infarction. Circulation. 1990; 82: 1147–58. https://doi.org/10.1161/01.CIR.82.4.1147

Kyriakidis M, Antonopoulos A, Barbetseas J, Aspioris N, Georgiakodis F, Sfikakis P, et al. Correlation of reciprocal ST-segment depression after acute myocardial infarction with coronary angiographic findings. Int J Cardiol. 1992; 36: 163–8. https://doi.org/10.1016/0167-5273(92)90003-L

Koju R, Islam N, Rahman A, Mohsin K, Ali A, Islam M, Yadav C. Electrocardiographic prediction of left anterior descending coronary artery occlusion site in acute anterior myocardial infarction. Nepal Med Coll J. 2003 Dec; 5(2):64-8. PMID: 15024768.

Zimetbaum PJ, Krishnan S, Gold A, Carrozza JP, Josephson ME. Usefulness of ST-segment elevation in lead III exceeding that of lead II for identifying the location of the totally occluded coronary artery in inferior wall myocardial infarction. Am J Cardiol. 1998; 81: 918–919. https://doi. org/10.1016/S0002-9149(98)00013-7

Chia BL, Yip JW, Tan HC, Lim YT. Usefulness of ST elevation II/III ratio and ST deviation in lead I for identifying the culprit artery in inferior wall acute myocardial infarction. Am J Cardiol. 2000; 86: 341–3. https://doi.org/10.1016/ S0002-9149(00)00929-2

Huey BL, Beller GA, Kaiser DL, Gibson RS. A comprehensive analysis of myocardial infarction due to left circumflex artery occlusion: comparison with infarction due to right coronary artery and left anterior descending artery occlusion. J Am Coll Cardiol. 1988; 12: 1156–1166. https://doi. org/10.1016/0735-1097(88)92594-6

Kontos MC, Desai PV, Jesse RL, Ornato JP. Usefulness of the admission electrocardiogram for identifying the infarctrelated artery in inferior wall acute myocardial infarction. Am J Cardiol. 1997; 79: 182–184. https://doi.org/10.1016/ S0002-9149(96)00709-6