Introduction: Intrauterine growth restriction is the second most common cause of perinatal mortality and morbidity after prematurity. Etiologies can be maternal, fetal or placental. The correct detection of compromised IUGR fetus to allow timely intervention is a main objective of antenatal care. Many of IUGR patients presents in their third trimester for the first time for antenatal examination. Such patients warrant a highly sensitive and specific diagnostic test which can be noninvasively applied on a large scale. Apart from various other non-invasive tests like USG, NST, Doppler flow studies give us vital information regarding the fetus in utero. Hence the present study is aimed at exploring the association of colour Doppler and non-stress test findings with the perinatal outcome in the fetuses with IUGR. Aim: To study relationship of Doppler and NST with perinatal outcome in IUGR cases. Material and Methods: A Prospective observational study was conducted on 70 patients of IUGR from August 2013 to November 2015 in Department of Obstetrics and Gynaecology , Dr. Vasantrao Pawar Medical College, Hospital & Research Center. Inclusion criteria: Patients with diagnosed singleton pregnancies with IUGR at gestational age more than 32weeks not in labour. Exclusion criteria: Patients with congenital anomalous fetus, diabetes or acute placental insult. Patients were followed up with serial Umbilical artery Doppler and NST. Perinatal outcome was correlated with the last Doppler and NST within 7days prior to delivery. Results: Perinatal outcome is worst in patients with both NST and Doppler are abnormal and best among patients with both normal NST and Doppler. Conclusion: Doppler predicts fetal compromise earlier as compared to NST.
Intrauterine Growth Restriction, Non-Stress Test, Umbilical Artery Doppler
Obstetrics and Gynaecology
American college of Obstetricians and Gynecologists. Intrauterine growth restriction. ACOG practice bulletin no.12. Washington DC. American college of Obstetricians and Gynaecologists. 2000.
Militello M, Pappalardo EM, Ermito S, Dinatale A, Cavaliere A, et al. Obstetric Management of IUGR. J Prenat Med. 2009; 36–9.
Briana DD, Malamitsi-Puchner A. Intrauterine growth restriction and adult disease: the role of adipocytokines. Eur J Endocrinol. 2009 Mar; 160(3):337–47.
Lakhkar BN, Rajagopal KV, Gourisankar PT. Doppler Prediction of Adverse Perinatal Outcome in PIH and IUGR. 2005 Feb; 109–16.
Malik R, Saxena A. Role of Colour Doppler Indices in the Diagnosis of Intrauterine Growth Retardation in High- Risk Pregnancies. J Obstet Gynecol India. 2012 Aug 17; 63(1):37–44.
Yelikar K, Prabhu A, Thakre GG. Role of Fetal Doppler and Non-Stress Test in Preeclampsia and Intrauterine Growth Restriction. J Obstet Gynecol India. 2013 Apr 11; 63(3):168–72.
Gomathi V, Mythili K. Colour Doppler verses NST in predicting Perinatal Outcome in Severe Preeclampsia and Fetal Growth Restriction. Journal of Evolution of Medical and Dental Sciences. 2015 May 14; 4(39):6804–10.
Radhika P, Rai L. Fetal Doppler verses NST as Predictors of Adverse Perinatal outcome in Preeclampsia and IUGR. J Obstet Gynecol India. 2006; 56:134–8.