Spectrum, Complications and Outcome of Acute Pediatric Poisoning


Abstract

This prospective study was aimed to study pattern and outcome of childhood poisoning at a tertiary care centre in North India. All pediatric patients admitted with poisoning during 2012 and 2013 were included, and socio-demographic and clinical details of the patients recorded. Acute poisoning was reported in 104 children aged 9 months to 16 years during the study period. They constituted 2.6% of total pediatric admissions during the period. Males were 58 (56%) and females 46 (44%). The mean age was 5 years (9 months-16 years). Poisoning was suicidal in 11 (10.6%) and accidental in 93 (89.4%). Cholinesterase inhibitor (ChEI) compounds (n = 27, 26%) and kerosene (n = 23, 21%) were the most common agents responsible for poisoning. ChEI poisoning and snake envenomation were associated with more complications. Overall mortality was 5 (4.8%); 4 patients died of ChEI poisoning and one of snake bite. In ChEI poisoning patients, mortality was higher in patients who had suicidal poisoning, seizures or required mechanical ventilation.

Keywords

Complications, Organophosphorus, Pediatric, Poisoning.

Subject Discipline

Pharmacy and Pharmacology

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