Safety/Toxicity studies of Ayurvedic formulation-Navratna rasa


Affiliations

  • Central Council for Research in Ayurveda and Siddha, Janakpuri, New Delhi, 110058, India
  • CCRAS Pharmacological Research Unit, (G.A.U.), Jamnagar, India

Abstract

Navratna rasa, an ayurvedic proprietary medicine based on classical formulation has been in use since long for general debility, rickets and calcium deficiency in Ayurvedic practices. The drug was screened for its safety/toxicity studies in acute and chronic models. No mortality and behavioral changes were observed during the course of acute toxicity study. The chronic toxicity study reveals that, the test drug has no serious toxicity potential to most of the important organs in therapeutics doses.

Keywords

Ayurvedic drug, toxicity, rats

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References

Kenaway, M.M., Hafez, M.A.H., Akl, M.A. and Lashein, R.R. (2000). Determination by AAS of some Trace heavy metal ions in some Natural and Biological samples after their preconcentration using Newly chemically modified chlormethylated polystyrene- PANION Exchanger. Anal.Sci., 16(5): 493.

Saper, R.B., Kales, S.N., Paquin, J., Barns, M.J., Eisenberg, D.M., Davis, R.B. and Phillips, R.S. (2004). Heavy metal content of Ayurvedic herbal medicine products. JAMA, 292: 2868-2873.

Paget, G.E. and Branes, G.M.(1964). Evaluation of Drug Activities: Pharmacometrics eds, Laurance and Bacharach, Vol.1. Academic Press, New York.

WHO (2004). Guidelines for Quality standardized herbal formulations.


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