Toxicity studies on a Unani herbal formulation "Capsule Hudar” in albino rats

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Authors

  • Seema Akbar
     Regional Research Institute of Unani Medicine, University of Kashmir Campus, Srinagar 190 006 JK ,IN
  • A. Masood
     Department of Biochemistry, University of Kashmir Campus, Srinagar 190 006 JK ,IN
  • Shamshad A. Khan
     Central Council for Research in Unani Medicine, New Delhi ,IN
  • Showkat Ali
     Regional Research Institute of Unani Medicine, University of Kashmir Campus, Srinagar 190 006 JK ,IN

Keywords:

capsule hudar, detoxification, strychnine, strychnos nux vomica, Unani herbal formulation

Abstract

Capsule Hudar, a very effective compound formulation of Unani System of Medicine, contains Azraqi (Strychnos nux vomica) a deadly poison as one of its constituents. However, it (Strychnos nux vomica) is detoxified, using a classical crude method, before its use to prepare the drug. Results on the evaluation of the drug at dose rate of 5 mg/kg body weight, orally as aqueous extract for 60 days in either sex for its toxicity in Wistar albino rats (150 ± 10g body weight) did not show any significant change in the blood glucose, blood urea and blood urea nitrogen and serum albumin and proteins levels. The activities of GOT/GPT and ACP/ALP levels in serum, brain, kidney, liver and spleen were also not significantly different when compared to controls.

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Published

2018-04-06

How to Cite

Akbar, S., Masood, A., Khan, S. A., & Ali, S. (2018). Toxicity studies on a Unani herbal formulation "Capsule Hudar” in albino rats. Toxicology International, 16(2), 107–110. Retrieved from http://informaticsjournals.com/index.php/toxi/article/view/20866

Issue

Volume 16, Issue 2, May-August 2009

Section

Original Research
Received 2018-04-06
Accepted 2018-04-06
Published 2018-04-06

 

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