Sero-biochemical Studies in Sheep Fed with Bt Cotton Plants


Affiliations

  • College of Veterinary Science, Hyderabad, Departments of Pharmacology and Toxicology, Andhra Pradesh, India
  • College of Veterinary Science, Hyderabad, Veterinary Pathology, Andhra Pradesh, India
  • College of Veterinary Science, Hyderabad, Livestock Research Institute, Andhra Pradesh, India
  • College of Veterinary Science, Hyderabad, Department of Animal Nutrition, Andhra Pradesh, India

Abstract

An experimental study was conducted to evaluate the toxicological effects, if any, due to feeding of Bt (Bacillus thuringiensis) cotton plants to sheep. A total of 32 sheep of one year of age belonging to Deccani breed were randomly divided into four groups, consisting of eight sheep in each group. Group 1 was maintained on basal diet (concentrate feed at the rate of 300 g + green fodder at the rate of 3 kg/sheep/day), group 2 on non-Bt cotton plant at the rate of 1.5 kg + green fodder at the rate of 1.5 kg + concentrate feed at the rate of 300 g/ sheep/day, group 3 on Bt cotton plants (50%) at the rate of 1.5 kg + green fodder at the rate of 1.5 + concentrate feed at the rate of 300 g/sheep/day, and group 4 on Bt cotton plants ad libitum + concentrate feed at the rate of 300 g/sheep/day. All the groups of sheep were maintained for three months and various hemato-biochemical parameters were studied at monthly intervals. The activity of aspartate transaminase, gamma glutamyltransferase, and creatine kinase in sera samples, and the concentration of blood urea nitrogen and creatinine did not differ significantly among different groups at different time intervals. The histological examination of liver and kidney did not reveal any significant changes in Bt and non-Bt cotton-fed groups. In conclusion, the results of the present investigation enunciated that feeding of genetically modified (Bt) cotton plants to sheep was without detrimental effects in the biological system of sheep.

Keywords

Bt cotton, sero-biochemistry, sheep

Subject Discipline

Zoology

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References

Reiser R, Fu HC. The mechanism of gossypol detoxification by ruminant animals. J Nutr 1962;76:215-8.

Betz FS, Hammond BG, Fuchs RL. Safety and advantages of Bacillus thuringiensis-protected plants to control insect pests. Regul Toxicol Pharmacol 2000;32:156-73.

Anonymous (2007). News paper reports: Deccan Herald, February 7, 2007; The Hindu, March 2, 2007; GM Watch, March 4, 2007; Hindustan Times, June 17, 2007; GM Watch, June 18, 2007; Hindustan Times, June 18, 2007.

Kaneko JJ, Harvey JW, Michael LB. Clinical Biochemistry of Domestic Animals. 5th ed. New York: Academic Press; 1997. p. 182-9, 857-79.

Boyd JW. Creatine phosphokinase in normal sheep and in sheep with nutritional muscular dystrophy. J Comp Pathol 1976;86:23-8.


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