In Vitro Anti-oxidant Effect of Vitamin E on Oxidative Stress Induced due to Pesticides in Rat Erythrocytes

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Authors

  • Ronika Saxena
     Department of Chemistry, Bareilly College, Bareilly - 243 005, Uttar Pradesh ,IN
  • Poonam Garg
     Department of Chemistry, Bareilly College, Bareilly - 243 005, Uttar Pradesh ,IN
  • D. K. Jain
     Department of Zoology, Bareilly College, Bareilly - 243 005, Uttar Pradesh ,IN

Keywords:

Catalase, chlorphyrifos, endosulfan, erythrocytes, lipid peroxidation, superoxide dismutase, vitamin E
Genetics

Abstract

An attempt was made to study the antioxidant property of vitamin E in endosulfan and chlorpyrifos toxicity. Erythrocytes were collected from healthy rats and exposed to 1 ppm endosulfan and chlorpyrifos pesticides individually and also along with vitamin E treatment. Results showed that endosulfan was more toxic in comparison of chlorpyrifos. Activities of superoxide dismutase and catalase were significantly decreased, while lipid peroxidation and glutathione-S-transfarase were increased in comparison to the control values. The results of the present study suggest that vitamin E acts as an effective antioxidant for endosulfan and chlorpyrifos pesticide toxicity, in reducing oxidative stress burden.

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Published

2018-05-21

How to Cite

Saxena, R., Garg, P., & Jain, D. K. (2018). <i>In Vitro</i> Anti-oxidant Effect of Vitamin E on Oxidative Stress Induced due to Pesticides in Rat Erythrocytes. Toxicology International, 18(1), 73–76. Retrieved from http://informaticsjournals.com/index.php/toxi/article/view/21317

Issue

Volume 18, Issue 1, January-June 2011

Section

Original Research
Received 2018-05-21
Accepted 2018-05-21
Published 2018-05-21

 

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