Hematobiochemical Evaluation of Dermal Subacute Cypermethrin Toxicity in Buffalo Calves

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Authors

  • Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab ,IN
  • Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab ,IN
  • Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab ,IN

Keywords:

Biochemical, buffalo calves, cypermethrin, dermal, hematology, toxicity
Endodontics

Abstract

Dermal exposure of cypermethrin, a type II synthetic pyrethroid insecticide, at dose rate of 0.25% for 14 consecutive days produced mild signs of toxicity in buffalo calves. It produced significant elevation in the levels of alanine aminotransferase (ALT; 39.5%), aspartate aminotransferase (AST; 32.0%), blood urea nitrogen (BUN; 57.7%), and plasma creatinine (30.0%). Cypermethrin also produced significant decrease in the hemoglobin (Hb) concentration (5.4%), packed cell volume (PCV; 3.4%), and total erythrocytic count (4.0%). Additionally, there was a significant increase in erythrocytic sedimentation rate (ESR; 3.1%). On the basis of the present study, it can be concluded that cypermethrin induces significant biochemical and hematological alterations in buffalo calves when exposed dermally.

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Published

2018-06-04

How to Cite

Dar, S. A., Kaur, R., & Kaur, R. (2018). Hematobiochemical Evaluation of Dermal Subacute Cypermethrin Toxicity in Buffalo Calves. Toxicology International, 21(3), 283–287. Retrieved from http://informaticsjournals.com/index.php/toxi/article/view/21409

Issue

Section

Original Research
Received 2018-06-01
Accepted 2018-06-01
Published 2018-06-04

 

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