Effects of Metformin on High-Fat Diet-Induced Hyperlipidemic Rats
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References
Dipiro JT, Wells BG, Schwinghammer TL, Dipiro CV.Pharmacotherapy Handbook (seventh ed). New York: Mc Graw Hill; 2015.
World Health Organization. Global Health Observatory (GHO) data Raised cholesterol [internet]. 2019 [cited 2 Feb 2019]. Available from: https://www.who.int/gho/ncd/ risk_factors/cholesterol_text/en/.
Kemenkes RI. Laporan Nasional Riskesdas 2018. Badan Penelitian dan Pengembangan Kesehatan; 2018.
Whalen K, Finkel R, Panavelil TA. Lippincott illustrated reviews : Pharmacology. (R. Finkel & T. A. Panavelil, Eds.) (sixth edit). Philadelphia: Wolters Kluwer Health; 2015.
Wulffele MG, Kooy A, Zeeuw DDE, Stehouwer CDA, Gansevoort RT. The effect of metformin on blood pressure, plasma cholesterol and triglycerides in type 2 diabetes mellitus: A systematic review. Journal of Internal Medicine.2004; 256(1):1–14. https://doi.org/10.1111/j.13652796.2004.01328.x. PMid:15189360.
Kashi Z, Mahrooz A, Kianmehr A, Alizadeh A. The role of metformin response in lipid metabolism in patients with recent-onset type 2 diabetes: HbA1c level as a criterion for designating patients as responders or nonresponders to metformin. PLOS ONE; 2016. p. 1–10. https://doi.org/10.1371/journal.pone.0151543. PMid:26978661 PMCid:PMC4792461
Al-jabouri NHM. Effects of oral hypoglycemic drugs on serum lipid profile in hyperlipidemic rats. 2013; 10(1);245–56.
Deepika MY, Devi MARL, Nagaraju B, Deepthi PR, Bakshi BV. Anti obesity activity and beneficial effects of methanolic extract of desmostachya bipinnata in hfd and progesterone induced obesity in rats and mice. International Journal of Pharmaceutical Science and Research. 2016; 7(11):4644–55.
Wardani E. Studi Interaksi Farmakodinamika dan Farmakokinetika Simvastatin dengan EkstrakDaun Kemuning (Murraya paniculata L.) sebagaiAntihiperlipidemia [disertasi]. Depok: Universitas Indonesia; 2019.
Hasimun P, Sukandar E, Adnyana I, Tjahjono D. A simple method for screening antihyperlipidemic agents.International Journal of Pharmacology. 2011; 7(1):74–8.https://doi.org/10.3923/ijp.2011.74.78.
Li S, Jin S, Song C, Chen C, Zhang Y, Xiang Y, Jiang H.The metabolic change of serum lysophosphatidylcholines involved in the lipid lowering effect of triterpenes from Alismatis rhizoma on high-fat diet induced hyperlipidemia mice. Journal of Ethnopharmacology. 2016; 177:10–18.https://doi.org/10.1016/j.jep.2015.11.017. PMid:26584875.
Kusuma AM, Asarina Y, Rahmawati YI, Susanti S. Efek ekstrak bawang dayak (Eleutherine palmifolia (L.)Merr) dan Ubi Ungu (Ipomoea batatas L) terhadap penurunan kadar kolesterol dan trigliserida darah pada tikus jantan.Jurnal Kefarmasian Indonesia. 2017; 6(2):108–16. https:// doi.org/10.22435/jki.v6i2.6225.108-116.
Duntas LH, Brenta G. A renewed focus on the association between thyroid hormones and lipid metabolism. Frontiers in Endocrinology. 2018; 9(Sep). https://doi.org/10.3389/ fendo.2018.00511. PMid:30233497 PMCid:PMC6129606.
Malin SK, Kashyap SR. Effects of metformin on weight loss: Potential mechanisms. Current Opinion in Endocrinology and Diabetes and Obesity. 2014; 21(5):323–9. https://doi.org/10.1097/MED.0000000000000095. PMid:25105996.
van Stee MF, de Graaf AA, Groen AK. Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy. Cardiovascular Diabetology. 2018; 17(1):1-22. https://doi.org/10.1186/ s12933-018-0738-4. PMid:29960584 PMCid:PMC6026339.
Rena G, Hardie DG, Pearson ER. The mechanisms of action of metformin. Diabetologia. 2017; 60(9):1577–85. https:// doi.org/10.1007/s00125-017-4342-z. PMid:28776086.PMCid:PMC5552828.
Lv WS, Wen JP, Li L, Sun RX, Wang J, Xian YX, Gao YY.The effect of metformin on food intake and its potential role in hypothalamic regulation in obese diabetic rats. Brain Research. 2012; 1444:11–19. https://doi.org/10.1016/j.brainres.2012.01.028. PMid:22325091.
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