Assessment of Genotoxicity of Cassia auriculata Flower Powder
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Authors
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Department of Biomedical Engineering, Velalar College of Engineering and Technology, Erode – 638012 ,IN
N. Jeyashanthi -
Department of Biomedical Engineering, Velalar College of Engineering and Technology, Erode – 638012 ,INP. Ravikumar
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Department of Biomedical Engineering, Velalar College of Engineering and Technology, Erode – 638012 ,INN. N. Baalakumar
DOI:
https://doi.org/10.15613/fijrfn/2017/v4i2/167615Keywords:
Aqueous Extract, Cassia auriculata, Mutagenicity, Salmonella typhimurium.Abstract
The flower of Cassia auriculata commonly used for treatment, especially in Ayurvedic medicine in India was tested for mutagenicity by the Ames test using Salmonella typhimurium TA 98, TA 100 and TA 102 strains. The genotoxicity assessment of flower powder of Cassia auriculata was performed in aqueous extract 1:10. The flower powder of Cassia auriculata did not induce any frame shift mutation in the strain TA 98, which indicates its antimutagenic effect and did not cause any base pair substitution at the dose level tested 100μg/plate. The colony counts in all the three strains were found close to the spontaneous revertants frequency showing that flower powder of Cassia auriculata is antimutagenic at the dose level tested (100μg/plate).
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