Progestin as an Inhibitor of Premature Ovulation through LH Suppression in IVF
Authors
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Department of Zoology, Dinabandhu Andrews College, Kolkata - 700084, West Bengal ,IN
Joydeep Das -
Department of Zoology, Dinabandhu Andrews College, Kolkata - 700084, West Bengal ,INBanani Bindhani
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Department of Zoology, Dinabandhu Andrews College, Kolkata - 700084, West Bengal ,INSneha Maity
DOI:
https://doi.org/10.18311/jer/2022/30705Keywords:
GnRH Analogue, IVF, Progestin, PPOSAbstract
Progestin is a synthetic form of progesterone hormone. Progestin is used as a contraceptive pill. Progestin can suppress
endogenous Luteinizing Hormone (LH) secretion from the pituitary. Premature ovulation in Assisted Reproductive
Technology (ART)can be prevented by taking progestin. Progestin–Primed Ovarian Stimulation (PPOS) is now widely used
for the treatment of infertility through IVF. Progestin pills are more effective than GnRH analogue for patients. Progestins
are an excellent alternative to antagonists. PPOS is slightly more advantageous than the Controlled Ovarian Stimulation
(COS) protocol. Progesterone regulates follicular growth through PI3K/AKT and MAPK signaling pathway.
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