Antiulcer Activity of Aqueous Extract of Basella rubra in Albino Rats


Affiliations

  • K. B. Institute of Pharmaceutical Education and Research, Gandhinagar, Gujarat, 382023, India
  • Ayushri Panchakarma Clinic, Ahmedabad, Gujarat, 380015, India
  • Nirma University, Department of Science and Technology, Institute of Pharmaceutical Sciences, Ahmedabad, Gujarat, 382481, India

Abstract

Objective: To evaluate the antiulcer activity of aqueous extract of Basella rubra. Materials and method: Aqueous extract of the leaves of Basella rubra was prepared and antiulcer activity was studied on ethanol and pylorus ligated induced gastric ulcers in rats. Results: Aqueous extract of the leaves of Basella rubra (10 and 20mg/kg p.o.) showed significant and dose-dependent antiulcer activity against ethanol and pylorus ligated induced ulcer in rats. Study was compared with ranitidine (50 mg/kg p.o.) as standard drug. Conclusion: The present results indicate the potential of aqueous extract of Basella rubra in the treatment of gastric ulcers.

Keywords

Basella rubra, Antiulcer Activity, Pylorus Ligation, Gastric Ulcer.

Subject Discipline

Pharmacy and Pharmacology

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