Cyclic Voltammetric Determination of Acetylsalicylic Acid (Aspirin) at Polyaniline (PANI) Modified Glassy Carbon Electrode


Affiliations

  • Haramaya University, Chemistry Department, Dire Dawa, Ethiopia
  • Haramaya University, Biology Department, Dire Dawa, Ethiopia

Abstract

Polyaniline (PANI)-modified glassy carbon electrode has been synthesized by electropolymerizing aniline for determining acetylsalicylic acid (ASA in pharmaceutical samples using cyclic and differential pulse voltammetric techniques. The best performance of the PANI modified glassy carbon electrode in 0.04 M Britton Robinson buffer was obtained at pH 2.0. Under these conditions single oxidation peak at a potential of 250 mV vs Ag/AgCl/sat'd KCl, characteristic of an irreversible reaction, was observed. Studies on the effects of pH, scan rate and substrate concentration revealed irreversible diffusion controlled electrode redox reaction. The PANI modified glassy carbon electrode showed higher electro-catalytic efficiency, compared to the unmodified one, for ASA determination.

Keywords

Aspirin, Electro-Catalytic Efficiency, Pharmaceutical, Polyaniline, Voltammetry.

Subject Discipline

Chemistry

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