Fibrin Glue Vs Vicryl (10-0) Suture in Limbo Conjunctival Autograft in the Management of Primary Pterygium : A Prospective Comparative Study


Affiliations

  • Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Department of Ophthalmology, Nashik, Maharashtra, 422003, India

Abstract

Background: Pterygium is a wing shaped fibrovascular tissues proliferation from the conjunctiva on to the cornea. There is no satisfactory treatment for pterygium available yet. Among the available treatments, surgical treatment is better than medical treatment. Pterygium excision with graft placement is the preferred technique. Here, a comparative study is done between graft placement by suture and glue technique. Aims and Objective: To compare fibrin glue and suture technique for the treatment of pterygium in terms of: 1. operation time. 2. Post operative comfort level 3. Recurrence. Material and Methods: Total of 60 patients with primary pterygium, 30 in each group with fibrin glue -Group A and 10-0 vicryl suture -Group B were taken in the study. The study was conducted between august 2014 to September 2016. Results: Mean operating time was 30 minutes in fibrin glue group and 47 minutes in suture group.post operative comfort level was significantly different in second follow up recurrence rate was 0 in both group. Conclusion: Fibrin glue is a better technique in terms of operating time and post operative comfort level of the patient.

Keywords

Fibrin Glue, Pterygium, Suture Technique

Full Text:

References

Zaky KS, Khalifa YM. Efficacy of preoperative injection versus intraoperative application of mitomycin in recurrent pterygium surgery. Indian J Ophthalmol. 2012; 60:273–6.https://doi.org/10.4103/0301-4738.98703 PMid:22824595 PMCid:PMC3442461

Tan DTH, Lein ASM. Abnormal expression of the P53 tumor expression gene in the conjunctiva of patients with pterygium.AJO. 1997; 123(3):404–5. https://doi.org/10.1016/ S0002-9394(14)70141-2

Chowers I, Pe’er J, Zamir E, Livni N, Ilsar M, Frucht-Pery J. Proliferative activity and p53 expression in primary and recurrent pterygia. Opthalmology. 2001 May; 108(5):985–8.https://doi.org/10.1016/S0161-6420(00)00651-5

Chui J, Di Girolamo N, Wakefield, Coroneo MT. The pathogenesis of pterygium current concepts and their therapeutic implications. Ocul Surf. 2008 Jan; 6(1):24–43. https://doi.org/10.1016/S1542-0124(12)70103-9

Majoros J. Conjunctival transplantation for treatment of pterygium. Am J Ophthalmol. 1950; 61:1289. https://doi.org/10.1016/0002-9394(50)91005-1

Kenyon KR., Wagoner MD., Hettinger ME. Conjunctival autograft transplantation for advanced and recurrent pterygium.Ophthalmology. 1985; 92:1451–70. https://doi.org/10.1016/S0161-6420(85)33831-9

Youngson RM. Recurrence of pterygium after excision.BJO. 1972; 56:120–5. https://doi.org/10.1136/bjo.56.2.120

Hirst LW. The treatment of pterygium. Surv Ophthalmol.2003; 48(2):145–80. https://doi.org/10.1016/S00396257(02)00463-0

Ang LP, Chua JL, Tan DT. Current concepts and techniques in pterygium treatment. Curr Opin Ophthalmol.2007; 18(4):308–313. https://doi.org/10.1097/ICU.0b013e3281a7ecbb PMid:17568207

Starck T, Kenyon KR, Serrano F. Conjunctival autograft for primary and recurrent pterygia: Surgical technique and problem management. Cornea. 1991; 10(3):196–202.https://doi.org/10.1097/00003226-199105000-00002 PMid:2055023

Rubin MR, Dantas PE, Nishiwaki-Dantas MC, Felberg S. Efficacy of fibrin tissues adhesive in the attachment of autogenous conjunctival graft on primary pterygium surgery. Arq Bras Oftalmol.2011; 74(2):123–6. https://doi.org/10.1590/ S0004-27492011000200011 PMid:21779669

Pan HW, Zhong JX, Jing CX. Comparision of fibrin glue versus suture for conjunctival autografting in pterygium surgery: A meta-analysis. Ophthlmology. 2011;118(6):1049– 54. https://doi.org/10.1016/j.ophtha.2010.10.033 PMid:21292327

Ti SE, Tseng SC. Management of primary and recurrent pterygium using amniotic membrane transplantation.Curr Opin Ophthalmol. 2002; 13(4):204. https://doi.org/10.1097/00055735-200208000-00003

Hirst LW, Sebban A, Chant D. Pterygium recurrence time. Ophthalmology 1994; 101(4):755–8. https://doi.org/10.1016/S0161-6420(94)31270-X

Kenyon KR, Wagoner MD, Hettinger ME. Conjunctival autograft transplantation for advanced and recurrent pterygium.Ophthalmology. 1985; 92:1451–70. https://doi.org/10.1016/S0161-6420(85)33831-9

Koranyi G, Seregard S, Kopp ED. The cut-and-paste method for primary pterygium surgery: Long term follow up.Acta Ophthalmol Scand. 2005; 83(3):298–301. https://doi.org/10.1111/j.1600-0420.2005.00465.x PMid:15948780

Nieuwendaal CP, van der Meulen IJ, Mouritis M, Lapid-Gortzak R. Long term follow up of pterygium surgery using conjunctival autograft and Tissucol. Cornea. 2011; 30(1):34–6. https://doi.org/10.1097/ICO.0b013e3181dea7f0

Coral-Ghanem R, Oliveria RF, Furlanetto E, Ghanem MA, Ghanem VC. Conjunctival autologus transplantation using fibrin glue in primary pterygium. Arq Bras Optalmol.2010; 73(4):350–3. https://doi.org/10.1590/S000427492010000400010

Shimazaki J, Yang H, Tsubota K. Limbal autograft transplantation for recurrent and advanced pterygia. Ophthalmic Surgery and Laser. 1996; 11:917–23.

Figueiredo RS, Cohen EJ, Gomes JAP, Rapuans CJ, Laibson PR. Conjunctival autograft for pterygium surgery: How well does it prevent recurrences? Ophthalmic Surgery Laser.1997; 28:99–104. PMid:9054479

Rao SK, Lekha T, Mukesh BN. Conjunctival limbal autografts for primary and recurrent pterygia: Technique and results. IJO. 1998; 46:203–9.

Varssano D, Michaeli-Cohen A, Loewenstein A. Excision of pterygium and conjunctival autograft. Isr Med Assoc J. 2002 Dec; 4(12):1097–100. PMid:12516899

Young AL, Leung GYS, Wong AKK, Cheng LL, Lam DS. CA randomised trial comparing 0.02% mitomycin C and limbal conjunctival autograft after excision of primary Pterygium.Br J Ophthalmol. 2004; 88:995–7. https://doi.org/10.1136/ bjo.2003.036830 PMid:15258011 PMCid:PMC1772290


Refbacks

  • There are currently no refbacks.