Acute Axonal Polyneuropathy in a Chronic Alcoholic Patient:A Rare Presentation

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Authors

  • Department of General Medicine, Nilratan Sircar Medical College and Hospital, Kolkata - 700 014, West Bengal ,IN
  • Department of Neurology, Nilratan Sircar Medical College and Hospital, Kolkata - 700 014, West Bengal ,IN
  • Department of General Medicine, Nilratan Sircar Medical College and Hospital, Kolkata - 700 014, West Bengal ,IN

Keywords:

Acute Motor Sensory Axonal Neuropathy, Acute Polyneuropathy, Alcoholic Neuropathy, Guillain Barre Syndrome.

Abstract

Guillain Barre Syndrome (GBS) is an acute inflammatory demyelinating polyradiculoneuropathy of autoimmune nature, characterized by rapidly progressive, symmetric weakness and areflexia. Acute motor sensory axonal neuropathy is a variant of GBS with motor paralysis, hyporeflexia/areflexia, and sensory loss. Alcohol produces central nervous system toxicity as its principal side effects. Alcoholic neuropathy is a mixed sensory and motor disorder affecting large and small fibers to varying degrees. In contrast to the classic, slowly progressive polyneuropathy in alcoholic patients, acute forms, clinically mimicking GBS, are rare. This is a case of a 37 year old chronic alcoholic lady presenting with subacute onset weakness of both lower limbs whose laboratory data indicate neuropathy of acute motor sensory axonal pattern. We emphasize that acute alcoholic neuropathy has to be distinguished from GBS and other forms of acute polyneuropathy by using clinical, laboratory, and electrophysiological data for therapeutic and prognostic concerns.

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Published

2015-08-01

How to Cite

Pal, S., Ghosal, A., & Biswas, N. M. (2015). Acute Axonal Polyneuropathy in a Chronic Alcoholic Patient:A Rare Presentation. Toxicology International, 22(2), 119–122. Retrieved from https://informaticsjournals.com/index.php/toxi/article/view/20268

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Section

Case Report