Biomedical Importance of the Gila Monster Venom

Jump To References Section

Authors

  • Rohan Khan
     Department of Zoology, Vidyasagar University, Midnapore – 721102, Dist. Paschim Medinipur, West Bengal ,IN
  • Subho Ghosh
     PG Department of Zoology, Midnapore College (Autonomous), Midnapore – 721101, Dist. Paschim Medinipur, West Bengal ,IN

DOI:

https://doi.org/10.24906/isc/2021/v35/i1/208414

Keywords:

Reptile, lizard, Gila Monster, Venom, Exendin, Natural Protein.

Abstract

Among vertebrates, the class Reptilia acquires a significant place for some of their distinctive features and one of them is production of poison or venom. One prominent example is the lizard known as Gila monster (Heloderma suspectum). Found in United States and North-West Mexican states of Sonora, these lizards have glands (that secretes poison), which are located on both sides of their lower jaw which is transferred through grooves along with their saliva.

Downloads

Download data is not yet available.

Downloads

Published

2021-01-01

How to Cite

Khan, R., & Ghosh, S. (2021). Biomedical Importance of the Gila Monster Venom. Indian Science Cruiser, 35(1), 21–24. https://doi.org/10.24906/isc/2021/v35/i1/208414

Issue

Volume 35, Issue 1, January 2021

Section

Search & Survey
Crossref
Scopus
Google Scholar
Europe PMC

 

References

D D Beck, Biology of Gila Monsters and Beaded Lizards, Vol 9, University of California Press 2, Animal Facts- Gerard Cheshire, 2005.

Deadly Lizard Spit that can Control Diabetes, The Times of India, 7th May 2007

M E Doyle and J M Egan, Mechanisms of Action of Glucagon-Like Peptide1 in the Pancreas, Pharmacology &Therapeutics, Vol 113, No 3, page 546-593, 2007.

R French, D Brooks, A M Ruha, F Shirazi, P Chase, K Boesen et al., Gila Monster (Heloderma Suspectum) Envenomation: Descriptive Analysis of Calls to United States Poison Centers with Focus on Arizona Cases, Clinical Toxicology, Vol 53, No 1, page 60-70, 2015.

C Guja, J P Frías, A Somogyi, S Jabbour, H Wang, E Hardy et al., Effect of Exenatide QW or Placebo, both Added to Titrated Insulin Glargine, in Uncontrolled Type 2 Diabetes: the Duration-7 Randomized Study, Diabetes, Obesity and Metabolism, 2018.

R J Mann, N E Nasr, J K Sinfield, E Paci, D Donnelly, The Major Determinant of Exendin-4/ Glucagon-Like Peptide 1 Differential Affinity at the Rat Glucagon-Like Peptide 1 Receptor N-Terminal Domain is a Hydrogen Bond from SER-32 of Exendin-4, British Journal of Pharmacology, Vol 160, No 8, page 1973-1984, 2010.

K W Sangaard, T F Dyrlund, L R Thomsen, T A Nielsen, L Brøndum, T Wang et al. Characterization of the Gila Monster (Heloderma Suspectum Suspectum) Venom Proteome, Journal of Proteomics, Vol 117, page 1-11, 2015.

Y Yin, X E Zhou, L Hou, L H Zhao, B Liu, G Wang et al., An Intrinsic Agonist Mechanism for Activation of Glucagon-Like Peptide-1 Receptor by Its Extracellular Domain, Cell Discovery, Vol 2, page 16042, 2016.