Clinical Spectrum and Epidemiology of Renal Diseases: Insights from Renal Biopsy: A Single Hospital Study

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Authors

  • Sant Kumar Pandey
     Chandan Institute of Renal Sciences and Kidney Transplant, Chandan Hospital, Lucknow – 226010, Uttar Pradesh ,IN
  • Dhairya Prakash Prajapati
     Chandan Institute of Renal Sciences and Kidney Transplant, Chandan Hospital, Lucknow – 226010, Uttar Pradesh ,IN
  • Amar Deep
     Department of Medical Gastroenterology, King George’s Medical University, Lucknow – 226003, Uttar Pradesh ,IN

Keywords:

C3 Glomerulopathy, Crescentic Glomerulo Nephritis (GN), FSGS (Focal and Segmental Glomerulonephritis), IgA N (IgA Nephropathy), MCD (Minimal Change Disease), MN (Membranous Nephropathy), MPGN (Membranoproliferative Glomerulonephritis)

Abstract

Introduction: Diagnosis of renal diseases through renal biopsy exhibits variability influenced by factors such as geographical location, ethnicity, age, gender and observer subjectivity. Aims: This study aimed to ascertain the frequency and distribution of various renal diseases diagnosed via renal biopsy at a tertiary care hospital in Lucknow, India. Materials and Methods: The study enrolled 187 patients who underwent renal biopsy between January 2020 and January 2023. Biopsies were conducted using percutaneous ultrasound-guided core needle biopsy, yielding two renal biopsy cores per patient. Results: The mean age of the patients was 35.7±16.8 years with a male predominance of 2.46:1. Primary glomerular diseases constituted 61.5% of cases, with IgA nephropathy as the most prevalent (21.4%), followed by focal and segmental glomerulonephritis (13.9%). Secondary glomerular diseases comprised 12.3% of cases with diabetic nephropathy being the most frequent (4.8%). Conclusion: The findings underscore the regional variability in renal disease patterns and highlight the crucial role of renal biopsy in accurate diagnosis and treatment decision-making. Further research is warranted to validate these observations and establish a national renal biopsy registry in India.

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Published

2024-05-16

How to Cite

Pandey, S. K., Prajapati, D. P., & Deep, A. (2024). Clinical Spectrum and Epidemiology of Renal Diseases: Insights from Renal Biopsy: A Single Hospital Study. Journal of Ecophysiology and Occupational Health. Retrieved from http://informaticsjournals.com/index.php/JEOH/article/view/42116

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Online First

Section

Research Article

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Copyright (c) 2024 Sant Kumar Pandey, Dhairya Prakash Prajapati, Amar Deep

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Received 2024-03-19
Accepted 2024-04-08
Published 2024-05-16

 

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