An In Vitro Study for Evaluating the Antimicrobial Efficacy of Polyherbal Combination Against Escherichia coli in the Management of Mutrakrichra (Urinary Tract Infection)

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Authors

  • Thakral Vidhi
     Department of Prasuti Tantra Evum Stri Roga, Parul Institute of Ayurved, Vadodara -391760, Gujarat ,IN
  • Karkare Manjusha
     Department of Prasuti Tantra Evum Stri Roga, Parul Institute of Ayurved, Vadodara -391760, Gujarat ,IN
  • Bhagat Lumi
     Department of Prasuti Tantra Evum Stri Roga, Parul Institute of Ayurved, Vadodara -391760, Gujarat ,IN
  • Mathad Prasanna
     Department of Rasa Shastra Evum Bhaishjya Kalpana, Parul Institute of Ayurved and Research, Vadodara - 391760, Gujarat ,IN
  • Patel Janki
     Department of Pharmaceutics, Parul Institute of Pharmacy and Research, Vadodara -391760, Gujarat ,IN

DOI:

https://doi.org/10.18311/jnr/2024/34473

Keywords:

Anti-bacterial Activity, Berberis aristata, Emblica officinalis, Escherichia coli, Honey, Mutrakrichra, Urinary Tract Infection

Abstract

Millions of people worldwide experience Urinary Tract Infections (UTIs), which rank among the most widespread bacterial infections. UTIs are a common health issue, particularly among women and certain populations. Escherichia coli is the most frequent pathogen, causing 75-90 % of UTIs. Timely diagnosis, appropriate treatment, and preventive measures can help reduce the burden of UTIs and minimize complications associated with these infections. In order to address this issue, classical formulations are mentioned in Ayurvedic texts. In the current study, hydroalcoholic extracts of Emblica officinalis (Amalaki) and Berberis aristata (Daruharidra) were prepared. The antimicrobial activity of the extracts and their combination was evaluated by establishing their Minimum Inhibitory Concentration (MIC) and measuring the zone of inhibition. The combination of Amalaki and Daruharidra with honey shows significant inhibition of E. coli which is comparable with tablet Norfloxacin. This study suggests that Emblica officinalis (Amalaki) and Berberis aristata (Daruharidra) can be used in Mutrakrichra associated with Mutradaha in the context of urinary tract infections.

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Published

2024-01-01

How to Cite

Thakral Vidhi, Karkare Manjusha, Bhagat Lumi, Mathad Prasanna, & Patel Janki. (2024). An <i>In Vitro</i> Study for Evaluating the Antimicrobial Efficacy of Polyherbal Combination Against <i>Escherichia coli</i> in the Management of <i>Mutrakrichra</i> (Urinary Tract Infection). Journal of Natural Remedies, 24(1), 193–197. https://doi.org/10.18311/jnr/2024/34473

Issue

Volume 24, Issue 1, January 2024

Section

Short Communication

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Copyright (c) 2024 Thakral Vidhi, Karkare Manjusha, Bhagat Lumi, Mathad Prasanna, Patel Janki (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Europe PMC
Received 2023-07-20
Accepted 2023-09-20
Published 2024-01-01

 

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