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Isolation and Characterization of Bioactive Moiety from Leaf Extract of Ipomoea mauritiana and Evaluation of Anti-Inflammatory Activity by Carrageenan Induced Rat Paw Edema Test


Affiliations

  • Yuvaraja's College, University of Mysore, Department of Microbiology, Mysuru, Karnataka, 570005, India
  • Manasa Gangothri, University of Mysore, Department of Studies in Microbiology, Mysuru, Karnataka, 570006, India
  • Manasa Gangothri, University of Mysore, Department of Studies in Zoology, Mysuru, Karnataka, 570006, India

Abstract

Ipomoea mauritiana Jacq. is a member of family Convolvulaceae and commonly called as Ksheervidari is widely used in various traditional medicines for the treatment of many diseases. In the present work the column fractions of leaf extracts of I. mauritiana obtained by Soxhlet exrtaction was subjected to TLC, column chromatography, HPLC and liquid chromatography and mass spectroscopy (LC-MS). The compounds like caffeic acid and β-amyric acetate were tentatively identified to be present in one of the purified fraction. The column fraction was also tested for anti-inflammatory activity by carrageenan induced rat paw edema assay. The column fraction tested showed a very good anti inflammatory activity.

Keywords

Anti Inflammatory Activity, Carrageenan Induced Rat Paw Edema Column, Chromatography, Ipomoea Mauritiana

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