Ethno-medicines for Mosquito Transmitted Diseases from South-western Nigeria


  • University of Ibadan, Department of Pharmacognosy, Faculty of Pharmacy, Ibada, Nigeria
  • University of Ibadan, Institute for Advance Medical Research and Training, College of Medicine, Ibadan, Nigeria
  • University of Ibadan, Department of Pharmacognosy, Faculty of Pharmacy, Ibadan, Nigeria


The present study presents an ethnobotanical survey of the plants used in the treatment of mosquito transmitted diseases in Egbeda, Oluyole, Ibadan South-East and Akinyele, Local Government Areas in Oyo State, Southwest Nigeria. The survey was conducted through interviews using semi structured questionnaires. Twenty-four respondents, comprising of Traditional Medicine Practitioners (TMPs), herbalists, herb sellers, and the elderly were interviewed. Fourteen (58.3%) of them were males while ten (41.7%) were females and their ages ranged from 28 to 65 years. The Use-Mentions index (UMi) was calculated for each plant. Thirty-seven plant species belonging to 25 families were found to be useful for the treatment of mosquito transmitted diseases in the study areas. Ethno-medicinal information gathered on the plants includes vernacular names, plant parts used, forms of application and method of administration. The most prominent plant family is Euphorbiaceae with four species, while Lamiaceae, Fabaceae, Meliaceae had three species each. Other plant families include Apocynaceae, Combretaceae, Cucurbitaceae, Asteraceae with two species each. In all, the commonest species among the recipes given by the respondents was Hyptis suaveolens having a UMi of 0.250. Ocimum gratissimum, Xylopia aethiopica, Chromolaena odorata, and Nicotiana tabacum all had UMi of 0.167each. The study plays an important role in documenting and conserving traditional knowledge on medicinal plants used in treating insect transmitted diseases.


Ethno-medicine, insect transmitted diseases, Oyo State, Nigeria.

Subject Discipline

Pharmacy and Pharmacology

Full Text:


World Health Organization. A global brief on vectorborne diseases. 2014. WHO/DCO/WHD/2014.1.

Hawes NH. Nature Cures. Mosquito borne infections. A-Z of Human Ailments and Natural foods. 2005.

Tanser FC, Pluess B, Lengeler C, Sharp BL. Indoor residual spraying for preventing malaria. Cochrane database of Systematic Reviews. 2007; 3:CD006657. DOI:10.1002/14651858.

Lengelar C. Insecticide treated bed nets and curtains for preventing malaria. Cochrane database of Systematic Reviews. 2004; 2.

Jacobson M, Crossby DG. Naturally occurring insecticides. New York: Marcel Dekker Inc.; 1971. p.585.

Hemingway J, Field L, Vontas J. Overview of insecticide resistance. Science. 2002; 298:96–7.

Anstrom DM, Zhou X, Kalk CN, Song B, Lan Q. Mosquitocidal properties of natural product compounds isolated from chinese herbs and synthetic analogs of curcumin. J Med Entomol. 2012; 49(2):350–5.

Govindarajan M, Karuppannan P. Mosquito larvicidal and ovicidal properties of Eclipta alba (L.) Hassk (Asteraceae) against chikungunya vector, Aedesaegypti (Linn.) (Diptera:Culicidae). Asian Pac J Trop Med. 2011; 4(1):24–8.

Patil SV, Patil CD, Salunkhe RB, Salunke BK. Larvicidal activities of six plant extracts against two mosquito species, Aedes aegypti and Anopheles stephensi. Trop Biomed. 2010;27(3):360–5.

Marimuthu G, Rajamohan S, Mohan R, Krishnamoorthy Y. Larvicidal and ovicidal properties of leaf and seed extracts of Delonix elata (L.) Gamble (family:Fabaceae) against malaria (Anopheles stephensi Liston) and dengue (Aedes aegypti) (Diptera: Culicidae) vector mosquitoes.Parasitol Res. 2012; 111(1):65–77.

Ghosh A, Chowdhury N, Chandra G. Plant extracts as potential mosquito larvicides. Indian J Med Res. 2012;135(5):581–98.

Ghosh A, Chowdhury N, Chandra G. Plant extracts as potential mosquito larvicides. Indian J Med Res. 2012;135(5):581–98.

Ukeh DA, Birkett MA, Pickett JA, Bowman AS, Luntz AJM. Repellent activity of alligator pepper, Aframomum melegueta, and ginger, Zingiber officinale, against the maize weevil, Sitophilus zeamais. Phytochemistry. 2009;70:751–8.

Akinyele JO, Ogungbite OA. Insecticdal activities of some medicinal plants against Sitophilus zeamais (Mot Schulsley) (Coleoptera: Curculionidae) on stored maize. Arch Phytopathol Plant Biotechnol. 2013; 46(10):1206–13.

Adebajo AC, Famuyiwa FG, John JD, Idem ES, Adeoye AO. Activities of some Nigerian medicinal plants against Aedes aegypti. Chinese Med. 2012; 3:151–6.

Hatil HE, Kamali L. Medicinal Plants in East and Central Africa: Challenges and Constraints. Ethnobot Leaflets.2009; 13:364–9.

Andrade-Cetto A. Ethnobotanical study of the medicinal plants Tlanchinol Hidalgo, Mexico. J Ethnopharmacol.2009; 122:163–71.

Okello J, Ssgawa P. Medicinal plants used by communities of Ngai subcounty, Apac district, northern Uganda. Afr J Ecol. 2007; 45(1):6–83.

Bekalo TH, Woodmatas SD, Woldemariam ZA. An ethnobotanical study of medicinal plants used by local people in the lowlands of Konsa Special Woreda, southern nations, nationalities and peoples regional state, Ethiopia.J Ethnobiol Ethnomed. 2009; 5:26–40.

Cheikhyoussef A, Shapi M, Matengu K, Ashekele HM. Ethnobotanical study of indigenous knowledge on medicinal plants use by traditional healers in Oshikoto region, Namibia. J Ethnobiol Ethnomed. 2011; 7:1–11.

Ogbe FMD, Erucegun OL, Uwagboe M. Plants used for female reproductive health care in Oredo local government area, Nigeria. Scientific Res Essay. 2009; 4(3):120–30.

Libman A, Bouamanivong S, Southavong B, Sydara K, Soejarto DD. Medicinal plants: An important asset to health care in a region of Central Laos. J Ethnopharmacol.2006; 106(3):303–11.

Sonibare MA, Abegunde RB. Ethnobotanical study of medicinal plants used by the Laniba village people in south western Nigeria. Afr J Pharm Pharmacol. 2012;6(24): 1726–32.

Roark RC. Some promising insecticidal plants. Econ Bot.1947; 1:437–45.

Sukumar K. Rerich MJ. Bobber CR. Botanical derivatives in mosquito control: A review. J Am Mosq Control ASSOC. 1991; 7:210–37.

Willcox ML, Bodeker G. Traditiona herbal medicines for malaria: clinical review. British Med J. 2004; 329:1156–9.

Ileke KD, Odeyemi OO, Ashamo MO. Insecticidal activity of Alstonia boonei De Wild powder against cowpea bruchiel, Callobruchis maculatus (Fab.) (Coleoptera: Chrysomelidae) in stored cowpea seeds. Int J Biol. 2012; 4(2):125–31.

Ileke KD, Ogungbite OC. Alstonia boonei De Wild oil extract in the management of mosquito (Anopheles gambiae), a vector of malaria disease. J Coastal Life Med.2015; 3(7):557–63.

Ademola IO, Eloff JN. In vitro anthelmintic effect of Anogeissus leiocarpus (DC.) Guill. & Perr. leaf extracts and fractions on developmental stages of Haemonchus Contortus. Afr J Tradit Complemen Alt Med. 2011;8(2):134–9.

Choi WS, Park BS, Lee YH, Jang DY, Yoon YH, Lee SE. Fumigant toxicities of essential oils and monoterpenes against Lycoriella mali adults. Crop Prot. 2006; 25:398–401.

Kebede Y, Gebre-Michael T, Balkew M. Laboratory and field evaluation of neem (Azadirachta indica A. Juss) and Chinaberry (Melia azedarach L.) oils as repellents against Phlebotomus orientalis and P. bergeroti (Diptera:Psychodidae) in Ethiopia. Acta Trop. 2010; 113(2):145–50.

Xu J, Fan QJ, Yin ZQ, Li XT, Du YH, et al. The preparation of neem oil microemulsion (Azadirachta indica) and the comparison of acaricidal time between neem oil microemulsion and other formulations in vitro. Vet Parasitol. 2010. Available from

Rathy MC, Sajith U, Hatilal CC. Plant diversity for mosquito control: A preliminary study. Int J Mosq Res.2015; 2(1):29–33.

Martinelli AH, Kappaun K, Ligabue-Braun R, et al. Structure-function studies on jaburetox, a recombinant insecticidal peptide derived from jack bean (Canavalia ensiformis) urease. Biochim Biophs Acta. 2014;1840(3):935–44.

Bouda H, Tapondjou LA, Fontem DA, Gumedzo MYD. Effect of essential oils from leaves of Ageratum conyzoides, Lantana camara and Chromolaena odorata on the mortality of Sitophilus zeamais (Coleoptera, Curculionidae). J Stored Prod Res. 2001; 37:103–9.

Jose AR, Adesina JM. Larvicidal efficacy of Cola gigantea, Malacantha alnifolia and Croton zambesicus extracts as phytoinsecticdes against malaria vector Anopheles stephensi (Diptera: Culicidae). J Mosq Res. 2015; 5(5):1–5.

Bossou AD, Mangelinck XS, Yedomonhan H, Boko PM, et al. Chemical composition and insecticidal activity of plant essential oils from Benin against Anopheles gambiae (Giles). Parasites and Vectors. 2013; 6:337.

Kihampa C, Joseph CC, Nkunya MHH, Magesa SM, et al. Larvicidal and IGR activity of extract of tanzanian plants against malaria vector mosquitoes. J Vector Borne Dis.2009; 46:145–50.

Facey PC, Porter RBR, Reese PB, Williams LAD. Biological activity and chemical composition of the essential oil from Jamaican Hyptis verticillata Jacq. J Agric Food Chem.2005; 53:4774–7.

Ilboudo Z, Dabiré LCB, Nébié RCH, et al. Biological activity and persistence of four essential oils towards the main pest of stored cowpeas, Callosobruchus maculatus (F.) (Coleoptera: Bruchidae). J Stored Prod Res. 2010;46:124–8.

Okigbo RN, Okeke JJ, Madu NC. Larvicidal effects of Azadirachta indica, Ocimum gratissimum and Hyptis suaveolens against mosquito larvae. J Agric Technol. 2010;6 (4):703–19.

Rahman AA, Gopalakrishnan G, Venkatesan P, Geetha K. Isolation and identification of mosquito larvicidal compound from Abutilon indicum (Linn.) Sweet. Parasitol Res. 2008; 102:981–8.

Guiterrez Jr. PM, Antepuesto AN, Eugenio BAL, Santos MFL. Larvicidal activity of selected plant extract against the Dengue vector Aedes aegypti mosquito. Int Res J Biol Sci. 2014; 3(4):23–32.

Maharaj R, Maharaj V, Crouch NR, Bhagwandin N, Folb PI, Pillay P, Gayaram R. Screening of selected ethnomedicinal plants from South Africa for larvicidal activity against the mosquito Anopheles arabiansis. Malar J. 2012; 11:320.

Verma RK, Verma SK. Phytochemical and termiticidal study of Lantana camara var. aculeata leaves. Fitoterapia.2006; 77:466–8.

Dass K, Mariappan P. Larvicidal activity of Lawsonia inermis and Murraya exotica leaves extract on filarial vector, Culex quinquefasciatus. Int J Mosq Res. 2014;1(2):25–7.

Owolabi MS, Padilla-Camberos E, Ogundajo AL, Ogunwande IA, et al. Insecticidal Activity and Chemical Composition of the Morinda lucida essential oil against Pulse Beetle Callosobruchus maculatus. The Sci World J.2014; 1–7.

Idoko JE, Adebayo RA. Efficacy of Single and Combined Leaf Powder of Nicotiana Tabacum L. [Solanales: Solanaceae] with Reduced Rates of Pirimiphos-Methylin Management of Sitophilus Zeamais Motschulsky [Coleoptera:Curculionidae]. J Agric Sci. 2011; 3(1):276– 80.

Akumefula MI, Onwusonye J, Osuji CN, Uzomba, Onyekuru DA, Akumefula FU, Ubaka K, Eziukwu C. Comparative assessment of the insecticidal potency of Tobacco leaves extract (Nicotiana tabacum), black pepper seeds (Uziza) extract (Piper guineense) and African pepper seeds (Uda) extract (Xylopia aethiopica). Chem Mater Res.2014; 9(6): 57–9.

Tchoumbougnang F, Dongmo PMJ, Sameza ML, Mbanjo EGN, Fotso GBT, Zollo PHA, Menut C. Activité larvicide sur Anopheles gambiae Giles et composition chimique des huiles essentielles extraites de quatre plantes cultivées au Cameroun. Biotechnol Agron Soc Environ. 2009;13(1):77–84.

Tatsadjieu NL, Yaouba A, Nukenine EN, Ngassoum MB, Mbofung CMF. Comparative study of the simultaneous action of three essential oils on Aspergillus flavus and Sitophilus zeamais Motsch. Food Control. 2010; 21:186–90.

Johnson L, Williams LAD, Roberts EV. An insecticidal and acaricidal polysulfide metabolite from the roots of Petiveria alliacea. Pest Manage Sci.1997; 50(3):228–32.

Adebayo TA, Olaifa JI, Akintola AJ, Ojo AO. Field control of peridomestic mosquitoes of medical importance with extracts of Petivera alliacea L. Ife J Sci. 2004; 6(1):6–9.

François T, Michel JDP, Lambert SM, Ndifor F, Vyry WNA, Henri AZP, Chantal M. Comparative essential oils composition and insecticidal effect of different tissues of Piper capense L., Piper guineense schum. et Thonn., Piper nigrum L. and Piper umbellatum L. grown in Cameroon. Afri J Biotechnol. 2009; 8:424–31.

Okunlola AI, Ofuya TI, Aladesanwa RD. Efficacy of plant extracts on major insect pests of selected leaf vegetables in southwestern Nigeria. Agric J. 2008; 3:181–4.

Shaalan EA, Canyon D, Younes MWF, Abdel-Wahab H, Mansour A. A review of botanical phytochemicals with mosquitocidal potential. Environ Int. 2005; 31:1149–66.

Gemeda N, Mokomen W, Lemma H, Tadele A, et al. Insecticidal activity of some traditionally used Ethiopian medicinal plants against sheep ked Melophagus ovinus. J Parasitol Res. 2011; 1–7.

Gbolade AA. Insecticidal use of medicinal plants growing in Nigeria. Phytomedicine 2000; 5(7):87–8.

Adeniyi SA, Orjiekwe CL, Ehiagbonare JE, Arimah BD. Preliminary phytochemical analysis and insecticidal activity of ethanolic extracts of four tropical plant (Vernonia amygdalina, Sida acuta, Ocimum gratissimum and Telfaria occidentalis) against beans weevil (Acanthscelides obtectus).Int J Phys Sci. 2010; 5(6):753–92.

Nguemtchouin MMG, Ngassoum MB, Ngamo LST, Gaudu X, Cretin M. Insecticidal formulation based on Xylopia aethiopica essential oil and kaolinite clay for maize protection. Crop Prot. 2010; 29:985–991.

Kishore N, Mishra BB, Tiwar VK, Tripathi V. A review on natural products with mosquitocidal potentials. Oppor Challe Scop Nat Prod. 2001; 335–65.

Arivoli S, Tennyson S. Mosquitocidal Activity of Hyptis suaveolens (L.) Poit (Lamiaceae) extracts againstAedes aegypti, Anopheles stephensi AndCulex quinquefasciatus (Diptera: Culicidae). Int J Recent Sci Res. 2011; 2(5):143–9.

Adaramoye OA, Sarkar J, Singh N, Meena S, Changkija B, Yadav PP, Kanojiya S, Sinha S. Antiproliferative Action of Xylopia aethiopica fruit extract on Human cervical cancer cells. Phytother Res. 2011; 25(10):1558–63.

Chalton A. Medicinal uses of tobacco in history. J Royal Soc Med. 2004; 97(6):292–6.

Soladoye MO, Adetayo MO, Chukwuma EC, Adetunji A. Ethnobotanical survey of plants used in the treatment of haemorrhoids in Southwestern Nigeria. Ann Biol Res.2010a; 1(4):1–15.

Soladoye MO, Chukwuma EC, Owa FP. An ‘avalanche’ of plant species for the traditional cure of diabetes mellitus in Southwestern Nigeria. J Nat Prod Plant Res. 2012;2(1):60–72.

Kadir MF, Bin-Sayeed MS, Shams T, Mia MMK. Ethnobotanical survey of medicinal plants used by Bangladeshitraditional health practitioners in the management of diabetes mellitus. J Ethnopharmacol. 2012; 144:605–11.

Tripathi AK, Upadhyay S. Repellent and insecticidal activities of Hyptis suaveolens (Lamiaceae) leaf essential oil against four stored-grain coleopteran pests. Int J Insect Sci. 2009; 29(4):219–28.

Aziba PI, Bass D, Elegbe Y. Pharmacological investigation of Ocimum gratissimum in rodent for analgesic activity.Phytother Res. 1999; 13:427–9.

Somova LI, Shode FO, Moodley K, Govender Y. Cardiovascular and diuretic activity of kaurene derivatives of Xylopia aethiopica and Alepidea amatymbica. J Ethnopharmacol. 2001; 77(2-3):165–74.

Adeleye A, Conubogu C, Ayolabi CI. Screening of crude extracts of twelve medicinal plants and wonder cure concoction used in Nigeria unorthodox medicine for activity against Mycobacterium tuberculosis from tuberculosis patients’ sputum. Afr J Biotechnol. 2008;7(18):3182–7.

Madeira SV, Matos FJ, Leal-Cardoso JH, Criddle DN. Relaxant effects of the essential oil of Ocimum gratissimum on isolated ileum of the guinea-pig. J Ethnopharmacol. 2002; 81:1–4.

Bhargava D, Mondal CX, Shivapuri JN, Mondal S, Kar S. Antioxidant Properties of the Leaves of Chromolaena odorata Linn. J Inst Med. 2013; 35(1):53–7.

Elujoba AA, Odeleye OM, Ogunyemi CM. Traditional medicine development for medical and dental primary health care delivery system in Africa. Afr J Trad CAM.2005; 2(1):46–61.

Adebayo JO, Krettli AU. Potential antimalarials from Nigerian plants: A review. J Ethopharmacol. 2011;133(2):289–302.

Ong KW, Hsu A, Sen L, Huang D, Tan B. Polyphenolsrich Vernonia amygdalina shows anti-diabetic effects in streptozotocin-induced diabetic rats. J Ethopharmacol.2011; 133(2):598–607.

Attah AF, O’Brien M, Koehbach J, Sonibare MA, Moody JO, Smith TJ, Gruber CW. Uterine contractility of plants used to facilitate childbirth in Nigerian ethnomedicine. J Ethnopharmacol. 2012; 143:377–82.


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