Clinical Study of Diagnosed Cases of Dengue Fever in Tertiary Care Hospital in North Maharashtra


  • Dr. Vasantrao Pawar Medical College Hospital & RC, Department of General Medicine, Nashik, 422003, India


Aims and Objective: To study the clinical presentations, laboratory profile, hematological complications and outcome of dengue fever. Materials and Methods: Descriptive study was carried which includes adult males and females who were serologically confirmed cases of dengue. These patients were assessed for their demographic features (age/sex etc.); clinical profile various signs and symptoms; labotrary profile; complications and outcome as mentioned in the proforma. Results: Total 56 patients studied. Out of 56 cases, the maximum number of cases, 22 (39.2%), belonged to the age group between 20 to 40 years. Thus the mean age of hospitalized patients was 31.2 ± 4.5 yrs. There were 33 (58.9%) males and 23 (41.1%) female patients. Majority were Dengue Hemorrhagic fever 20 (35.7%) and 8 (14.2%) were cases of severe dengue according to WHO guidelines. Fever was present in all patients. Two patients developed DIC and died. Conclusion: Patients with dengue syndrome showed varied clinical presentation. Symptoms and clinical signs are non specific. Most adults were positive for symptoms like fever, myalgia, arthralgia, and skin rash and bleeding.


Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF), Disseminated Intravascular Coagulation (DIC), Dengue Shock Syndrome (DSS), Nonstructural Protein 1 (NS1)

Subject Discipline

General Medicine

Full Text:


Bagcchi S. Dengue surveillance poor in India. The Lancet. Elsevier; 2015. p. 1228. PMid:26460646

Shepard DS, Halasa YA, Tyagi BK, Adhish SV, Nandan D, Karthiga KS, et al. Economic and disease burden of dengue Illness in India. American Journal of Tropical Medicine and Hygiene. 2014; 91:1235–42. PMid:25294616 PMCid:PMC4257651

Ukey P, Bondade S, Paunipagar P, Powar R, Akulwar S. Study of seroprevalence of dengue fever in central India. Indian J Community Med. Medknow Publications and Media Pvt Ltd.; 2010; 35(4):517.

Noisakran S, Perng GC. Alternate hypothesis on the pathogenesis of Dengue Hemorrhagic Fever (DHF)/Dengue Shock Syndrome (DSS) in dengue virus infection. Exp Biol Med (Maywood). 2008 Apr; 233(4):401–8. PMid:18367628

Singh N, Singh J. Original article clinical presentation of dengue outbreak 2015, Haryana, India- A prospective observational study. Ann Appl Bio-Sciences. 2016; 3(2):158–63.

Shah I, Deshpande GC, Tardeja PN. Outbreak of dengue in Mumbai and predictive markers for dengue shock syndrome. J Trop Pediatr. 2004 Oct; 50(5):301–5.

Pervin M, Tabassum S, Ali M, Mamun KZ, Islam N. Clinical and laboratory observations associated with the 2000 dengue outbreak in Dhaka, Bangladesh. Dengue Bull. 2004; 28:96–106.

World Health Organization, Special Programme for Research, Training in Tropical Diseases, World Health Organization. Department of Control of Neglected Tropical Diseases, World Health Organization. Epidemic PA. Dengue: Guidelines for diagnosis, treatment, prevention, and control. World Health Organization; 2009. p. 147.

Kalayanarooj S, Vaughn DW, Nimmannitya S, Green S, Suntayakorn S, Kunentrasai N, et al. Early clinical and laboratory indicators of acute dengue illness. J Infect Dis. 1997 Aug; 176(2):313–21. PMid:9237695

Shah GS, Islam S, Das BK. Clinical and laboratory profile of dengue infection in children. Kathmandu Univ Med J. 2006; 4(1):40–3.

Banerjee M, Chatterjee T, Choudhary GS, Srinivas V, Kataria VK. Dengue: A clinicohaematological profile. Med J Armed Forces India. 2008; 64(4):333–6. S0377-1237%2808%2980014-7

Kumar A, Rao CR, Pandit V, Shetty S, Bammigatti C, Samarasinghe CM. Clinical manifestations and trend of dengue cases admitted in a tertiary care hospital, udupi district, karnataka. Indian J community Med. Medknow Publications and Media Pvt. Ltd.; 2010 Jul; 35(3):386–90.

Yung C-F, Lee K-S, Thein T-L, Tan L-K, Gan VC, Wong JGX, et al. Dengue serotype-specific differences in clinical manifestation, laboratory parameters and risk of severe disease in adults, singapore. Am J Trop Med Hyg. The American Society of Tropical Medicine and Hygiene; 2015 May; 92(5):999–1005. PMid:25825386 PMCid:PMC4426593

Itha S, Kashyap R, Krishnani N, Saraswat VA, Choudhuri G, Aggarwal R. Profile of liver involvement in dengue virus infection. Natl Med J India. 2005; 18(3):127–30. PMid:16130612

Sai PMV, Dev B, Krishnan R. Role of ultrasound in dengue fever. Br J Radiol. 2005 May; 78(929):416–8. PMid:15845934

Thulkar S, Sharma S, Srivastava DN, Sharma SK, Berry M, Pandey RM. Sonographic findings in grade III dengue hemorrhagic fever in adults. J Clin Ultrasound. 2000 Jan; 28(1):34–7. 000012928:13C34::AID-JCU53E3.3.CO3B2-4

Navarrete-Espinosa J, Gomez-Dantes H, Celis-Quintal JG, Vazquez-Martinez JL. Clinical profile of dengue hemorrhagic fever cases in Mexico. Salud Publica Mex. 2005; 47(3):193–200. PMid:16104461


  • There are currently no refbacks.