Probiotics: New Developments and Prospects in Human Wellness
DOI:
https://doi.org/10.21048/IJND.2024.61.3.35889Keywords:
Probiotics, diabetes, gut health, anaphylaxis, functional foodAbstract
Probiotics are live bacteria that show the potential to promote human health, particularly by enhancing nutrient absorption, digestion, and overall gut microbiota health when taken in adequate proportions. Probiotic consumption has been shown to effectively manage inflammatory-irritable bowel syndrome, including symptoms such as diarrhoea and Crohn's disease. Additionally, probiotics increase the functioning of the gut barrier, which restricts the presence of harmful microorganisms and thus ultimately enhances the immune system. Obesity is a worldwide healthcare concern that is closely associated with several chronic illnesses such as diabetes and cardiovascular disease. Probiotic ingestion regulates insulin sensitivity, hence decreasing the likelihood of developing diabetes. As a result of advances in scientific knowledge, more novel strains can be found or genetically modified, and these strains can then be functionalized according to an individual's particular gut microbiota, opening up new pathways for therapeutic interventions. Because of increased health consciousness among individuals in modern society, foods that contain probiotics have experienced a surge in popularity in recent years. The regulatory agencies should establish regular recommendations for the evaluation of probiotic strains. These guidelines should include the methods of genotyping and screening, in addition to other labelling guidelines. This will assure the consumers' safety, quality and effectiveness of the foodstuffs. In addition, studies involving other fields of expertise, such as microbiologists, immunologists, biotechnologists, food scientists, and nutritionists, are required to achieve an all-encompassing comprehension of the complex associations that exist between probiotics and human health.
Downloads
Metrics
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Rahul Mehra, Arun Kumar Pandey, Suresh Kumar Chauhan , Shiv Kumar
This work is licensed under a Creative Commons Attribution 4.0 International License.
All the articles published in IJND are distributed under a creative commons license. The journal allows the author(s) to hold the copyright of their work (all usages allowed except for commercial purpose).
Please contact us at editor@informaticsglobal.com for permissions related to commercial use of the article(s).
References
Williams, N.T. Probiotics. Am. J. Health-Syst. Pharm., 2010, 67, 449-458.
Ouwehand, A.C., Salminen, S. and Isolauri, E. Probiotics: An overview of beneficial effects. Lactic acid bacteria: Genetics, Metabolism and Applications, 2002, 82, 279-289.
Soccol, C.R., de Souza Vandenberghe, L.P., Spier, M.R., Medeiros, A.B.P., Yamaguishi, C.T., Lindner, J.D.D., Pandey, A. and Thomaz-soccol, V. The potential of probiotics: A review. Food Technol. Biotechnol., 2010, 48, 413-434.
Dogra, T., Mehra, R., Kumar, H. and Thakur, M. Probiotic potential of lactic acid bacteria isolated from traditional fermented food “maleda” of Northern Indian state. AFST., 2021, 22, 54-61.
Ljungh, A. and Wadstrom, T. Lactic acid bacteria as probiotics. Curr. Iss. Intestinal Microbiol., 2006, 7, 73-90.
Quinto, E.J., Jiménez, P., Caro, I., Tejero, J., Mateo, J. and Girbés, T. Probiotic lactic acid bacteria: A review. Food. Nutr. Sci., 2014, 5, 1765.
Dicks, L. and Botes, M. Probiotic lactic acid bacteria in the gastro-intestinal tract: Health benefits, safety and mode of action. Beneficial Microbes, 2010, 1, 11-29.
Reuben, R.C., Roy, P.C., Sarkar, S.L., Alam, A.R.U., and Jahid, I.K. Characterization and evaluation of lactic acid bacteria from indigenous raw milk for potential probiotic properties. J. Dairy Sci., 2020, 103, 1223-1237.
Mehra, R., Garhwal, R., Sangwan, K., Guine, R.P.F., Lemos, E.T., Buttar, H.S., Visen, P.K.S., Kumar, N., Bhardwaj, A. and Kumar, H. Insights into the research trends on bovine colostrum: Beneficial health perspectives with special reference to manufacturing of functional foods and feed supplements. Nutr., 2022, 14, 659. doi:10.3390/nu14030659
Mehra, R., Kumar, S., Verma, N., Kumar, N., Singh, R., Bhardwaj, A., Nayan, V. and Kumar, H. Chemometric approaches to analyze the colostrum physicochemical and immunological (IgG) properties in the recently registered Himachali Pahari cow breed in India. LWT., 2021, 145, 111256. doi:10.1016/j.lwt.2021.111256
Mehra, R., Singh, R., Nayan, V., Buttar, H.S., Kumar, N., Kumar, S., Bhardwaj, A., Kaushik, R. and Kumar, H. Nutritional attributes of bovine colostrum components in human health and disease: A comprehensive review. Food Biosci., 2021, 40, 100907. doi:10.1016/j.fbio.2021.100907
Ozen, M. and Dinleyici, E.C. The history of probiotics: The untold story. Beneficial Microbes, 2015, 6, 159-165.
Gasbarrini, G., Bonvicini, F. and Gramenzi, A. Probiotics history. J. Clin. Gastroenterol., 2016, 50, S116-S119.
Chauhan, S., Powar, P. and Mehra, R. A review on nutritional advantages and nutraceutical properties of cow and goat milk. Int. J. Appl. Res., 2021, 7, 101-105. doi:10.22271/allresearch.2021.v7.i10b.9025
Didari, T., Solki, S., Mozaffari, S., Nikfar, S., Abdollahi M. A systematic review of the safety of probiotics. Expert Opinion on Drug Safety, 2014, 13, 227-239.
Mehra, R., Kumar, H., Kumar, N., Ranvir, S., Jana, A., Buttar, H.S., Telessy, T.G., Awuchi, C.G., Okpala, C.O.R., Korzeniowska, M. and Guine, R.P.F Whey proteins processing and emergent derivatives: An insight perspective from constituents, bioactivities, functionalities to therapeutic applications. J. Funct. Foods, 2021, 87, 104760. doi:10.1016/j.jff.2021.104760
Kaur, I.P., Chopra, K. and Saini, A. Probiotics: Potential pharmaceutical applications. Eur. J. Pharmac. Sci., 2002, 15, 1-9.
Misra, S., Mohanty, D. and Mohapatra, S. Applications of probiotics as a functional ingredient in food and gut health. J. Food Nutr. Res., 2019, 7, 213-223.
Dey, G. Non-dairy Probiotic Foods: Innovations and Market Trends. In: Innovations in Technologies for Fermented Food and Beverage Industries. Springer, 2018, 159-173.
Kechagia, M., Basoulis, D., Konstantopoulou, S., Dimitriadi, D., Gyftopoulou, K., Skarmoutsou, N. and Fakiri, E.M. Health benefits of probiotics: A review. ISRN Nutr., 2013, 2013, 1-7. doi:10.5402/2013/481651
Weichselbaum, E. Potential benefits of probiotics- main findings of an in-depth review. Br. J. Comm. Nurs., 2010, 15, 110-114. doi:10.12968/bjcn.2010.15.3.46897
Ouwehand, A. and Vesterlund, S. Health aspects of probiotics. Drugs: The Investigational Drugs J., 2003, 6, 573-580.
Smolyansky, J. Probiotics: A Historical Perspective. In: Bioactive foods in promoting health. Elsevier, 2010, 43-45.
Kerry, R.G., Patra, J.K., Gouda, S., Park, Y., Shin, H.S. and Das, G. Benefaction of probiotics for human health: A review. J. Food. Drug Analy., 2018, 26, 927-939.
Suvarna, V.C. and Boby, V.U. Probiotics in human health: A current assessment. Curr. Sci., 2005, 88, 1744-1748.
Gill, H.S. and Guarner, F. Probiotics and human health: A clinical perspective. Postgraduate Med. J., 2004, 80, 516-526.
Tuomola, E.M. and Salminen, S.J. Adhesion of some probiotic and dairy Lactobacillus strains to Caco-2 cell cultures. Int. J. Food Microbiol., 1998, 41, 45-51.
Gill, H. and Prasad, J. Probiotics, Immunomodulation, and Health Benefits. Bioactive Components of Milk, 2008, 423-454.
Goldin, B.R. and Gorbach, S.L. Probiotics for Humans. Probiotics, 1992, 355-376.
Vasiljevic, T. and Shah, N.P. Probiotics- from Metchnikoff to bioactives. Int. Dairy J., 2008, 18, 714-728.
Maleki, D. and Homayouni, A., Khalili, L. and Golkhalkhali, B. Probiotics in cancer prevention, updating the evidence. Probiotics, prebiotics, and aynbiotics: Bioactive Foods in Health Promotion, 2015, 781-791.
Sivamaruthi, B.S., Kesika, P. and Chaiyasut C. The role of probiotics in colorectal cancer management. Evid. Based Complement. Alternat. Med., 2020, 2020, 3535982.
Shah, N.J. and Swami, O.C. Role of probiotics in diabetes: A review of their rationale and efficacy. Diabet., 2017, 5, 104-110.
Marik, P.E. Colonic flora, probiotics, obesity and diabetes. Front. Endocrinol., 2012, 3, 87.
Barengolts, E., Smith, E.D., Reutrakul, S., Tonucci, L. and Anothaisintawee, T. The effect of probiotic yogurt on glycemic control in type 2 diabetes or obesity: A meta-analysis of nine randomized controlled trials. Nutr., 2019, 11, 671.
Trafalska, E. and Grzybowska, K. Probiotics- an alternative for antibiotics? Wiadomosci lekarskie (Warsaw, Poland: 1960). 2004, 57, 491-498.
Oak, S.J. and Jha, R. The effects of probiotics in lactose intolerance: A systematic review. Crit. Rev. Food Sci. Nutr., 2019, 59, 1675-1683.
Koirala, S. and Anal, A.K. Probiotics-based foods and beverages as future foods and their overall safety and regulatory claims. Future Foods, 2021, 3, 100013.
Lavermicocca, P. Highlights on new food research. Digestive and Liver Disease, 2006, 38, S295-S299.
Baniwal. P., Mehra, R., Kumar, N., Sharma, S. and Kumar, S. Cereals: Functional constituents and its health benefits. Pharma Innov., 2021, 10, 01-07. doi:10.22271/tpi.2021.v10.i3a.5681
Behera, S.S. and Panda, S.K. Ethnic and industrial probiotic foods and beverages: Efficacy and acceptance. Curr. Opin. Food Sci., 2020, 32, 29-36.
Bajagai, Y.S., Klieve, A.V., Dart, P.J. and Bryden, W.L. Probiotics in Animal Nutrition: Production, Impact and Regulation. FAO, 2016.
Chaucheyras-Durand, F. and Durand, H. Probiotics in animal nutrition and health. Beneficial Microbes, 2010, 1, 3-9.
Garhwal, R., Sangwan, K., Mehra, R., Kumar, N., Bhardwaj, A., Pal, Y., Buttar, H.S. and Kumar, H. A systematic review of the bioactive components, nutritional qualities and potential therapeutic applications of donkey milk. J. Equine Veterinary Sci., 2022, 115 104006. doi:10.1016/j.jevs.2022.104006
Musa, H.H., Wu, S.L., Zhu, C.H., Seri, H.I. and Zhu, G.Q. The potential benefits of probiotics in animal production and health. J. Anim. Vet. Adv., 2009, 8, 313-321.
Gatesoupe, F.J. The use of probiotics in aquaculture. Aquaculture, 1999, 180, 147-165.
Balcázar, J.L., De Blas, I., Ruiz-Zarzuela, I., Cunningham, D., Vendrell, D. and Múzquiz, J.L. The role of probiotics in aquaculture. Vet. Microbiol., 2006, 114, 173-186.
Mehra, R., Garhwal, R., Sangwan, K., Guine, R.P.F., Lemos, E.T., Buttar, H.S., Visen, P.K.S., Kumar, N., Bhardwaj, A. and Kumar, H. Insights into the research trends on bovine colostrum: Beneficial health perspectives with special reference to manufacturing of functional foods and feed supplements. Nutr., 2022, 14, 659. doi:10.3390/nu14030659
Sahu, M.K., Swarnakumar, N.S., Sivakumar, K., Thangaradjou, T. and Kannan, L. Probiotics in aquaculture: Importance and future perspectives. Ind. J. Microbiol., 2008, 48, 299-308.
Stanton, C., Gardiner, G., Meehan, H., Collins, K., Fitzgerald, G., Lynch, P.B. and Ross, R.P. Market potential for probiotics. The Am. J. Clin. Nutr., 2001, 73, 476s-483s.
Sharma, S., Arora, M. and Baldi, A. Probiotics in India: Current status and future prospects. Pharm Aspire., 2013, 1, 1-12.
Gao, Y., Wang, X., Xue, C. and Wei, Z. Latest developments in food-grade delivery systems for probiotics: A systematic review. Crit. Rev. Food Sci. Nutr., 2021, 63, 1-18.
Grover, S., Rashmi, H.M., Srivastava, A.K. and Batish, V.K. Probiotics for human health-new innovations and emerging trends. BioMed. Central., 2012, 4, 15.
de Brito Alves, J.L., de Oliveira, Y., de Sousa, V.P. and de Souza, E.L. Probiotics for humans: Current status and future prospects. In: New and Future Developments in Microbial Biotechnology and Bioengineering. Elsevier; 2020, 243-254.
Gadhiya, D., Patel, A. and Prajapati, J.B. Current trend and future prospective of functional probiotic milk chocolates and related products- A review. Czech. J. Food Sci., 2015, 33, 295-301.