A Study on Antimicrobial Activity of Bacopa monnieri Linn. Aerial Parts


Affiliations

  • Institute of Pharmacy and Technology, Cuttack, Orissa, 754202, India
  • Jadavpur University, Department of Pharmaceutical Technology, Kolkata, 700032, India

Abstract

Objective: To study the antimicrobial activity of the ethanolic extract of aerial parts of Bacopa monnieri Linn. Materials and methods: Minimum inhibitory concentration of the extract was performed by broth dilution method and the zone of inhibition was studied by agar disc diffusion method at concentrations of 2, 5 and 10 mg/ml in DMSO. Ciprofloxacin (5 μg/ml) and Cotrimazole (25 μg/ml) were used as reference controls for the antibacterial and antifungal studies respectively. Results: The results of MIC study revealed the antimicrobial activity of the extract against the tested strains of microorganisms between concentration ranges of 50 and 400 μg/ml. The results of zone of inhibition study revealed concentration dependant nature of the extract with better effectiveness against gram-positive bacteria than gram-negative bacteria. Conclusion: The present study indicates the potential usefulness of B. monnieri aerial parts in the treatment of various pathogenic diseases as mentioned in the Ayurvedic literature.

Keywords

Bacopa monnieri Linn., Antibacterial Activity, Antifungal Activity, Minimum Inhibitory Concentration, Zone of Inhibition.

Subject Discipline

Pharmacy and Pharmacology

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