Anti-Nociceptive and Anti-Inflammatory Effects of the Methanol Extract of Annona senegalensis Root Bark

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Authors

  • ,NG
  • ,NG
  • ,NG
  • ,NG

DOI:

https://doi.org/10.18311/jnr/2003/365

Keywords:

Annona senegalensis, Analgesia, Anti-Inflammatory, Rheumatism.
Therapeutic Drug Monitoring

Abstract

Objective: To investigate the antinociceptive and anti-inflammatory effect of Annona senegalensis in mice and rats. Materials and Methods: The analgesic effects of the methanolic extract were studied using acetic acid-induced writhing test, hot plate test and formalin test, while the anti-inflammatory effect was evaluated using the egg-albumin induced hind paw oedema in rats. Results: The methanolic extract exhibited antinociceptive activity against the acetic acid writhing test, hot plate test and the late phase of formaline induced nociception and significant anti-inflammatory activity. Conclusion: The analgesic and anti-inflammatory effect of the methanolic extract might be through peripheral mechanisms and thus justifying its folkloric use in the treatement of rheumatic pain.

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Published

2003-01-01

How to Cite

Adzu, B., Amos, S., Adamu, M., & Gamaniel, K. S. (2003). Anti-Nociceptive and Anti-Inflammatory Effects of the Methanol Extract of <I>Annona senegalensis</I> Root Bark. Journal of Natural Remedies, 3(1), 63–67. https://doi.org/10.18311/jnr/2003/365

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