Evaluation of the Pattern and Mechanism of Bony Invasion in Gingivobuccal Sulcus and Gingival Squamous Cell Carcinoma and its Correlation with the Regional Lymph Node Metastasis: A Histopathological Study

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Authors

  • Irengbam Vidyalakshmi
     Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Bangalore, Karnataka ,IN
  • Abhilash Pasare
     Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Bangalore, Karnataka ,IN
  • T. V. Narayan
     Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Bangalore, Karnataka ,IN
  • Chaitanya N. Babu
     Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Bangalore, Karnataka ,IN
  • Shobith Shetty
     Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Bangalore, Karnataka ,IN
  • B. V. Prakruthi
     Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Bangalore, Karnataka ,IN

Keywords:

Gingivobuccal complex, Erosive pattern, Invasive pattern
Oral and Maxillofacial Pathology

Abstract

Objective: The purpose of this study was to assess the frequency of bony invasion and to evaluate the pattern and mechanism of tumor invasion into the bone and its correlation with the regional lymph node metastasis in gingivobuccal sulcus (GBS) and gingival squamous cell carcinoma.
Study design: A prospective study in which 25 resected specimens of the jaws along with the associated lymph nodes of patients treated for GBS and gingival squamous cell carcinomas were evaluated for the frequency, pattern and mechanism of tumor invasion into the bone and the regional lymph node metastasis, using a light microscope.
Results: 8 of the 25 cases showed bony invasion, among which 5 (20%) showed invasive pattern of tumor invasion while 3 (12%) showed the erosive pattern into the bone. The main mechanism of bony invasion was via the cortical plate (20%) than the periodontal ligament (12%). Regional lymph node metastasis was seen in 6 of the 8 cases showing bony invasion. No significant correlation was found between any of the above parameters.
Conclusion: In our attempt to study the tumor invasion into the bone, we found no significant correlation between the pattern and mechanism of invasion and the regional lymph node metastasis. A possible treatment guide through our study to the surgeon from our side is to prevent aggressive resections and to preserve the integrity of the jaw and thus, to provide the maximum probability of cure and maintain the quality of life.

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Published

2018-09-18

How to Cite

Vidyalakshmi, I., Pasare, A., Narayan, T. V., Babu, C. N., Shetty, S., & Prakruthi, B. V. (2018). Evaluation of the Pattern and Mechanism of Bony Invasion in Gingivobuccal Sulcus and Gingival Squamous Cell Carcinoma and its Correlation with the Regional Lymph Node Metastasis: A Histopathological Study. Journal of Pierre Fauchard Academy (India Section), 31(2-4), 93–98. Retrieved from https://informaticsjournals.com/index.php/jpfa/article/view/21124

Issue

Volume 31, Issue 2-4, June - December 2017

Section

Original Articles

License

All the articles published in JPFA are distributed under a creative commons license. The journal allows the author(s) to hold the copyright of their work (all usages allowed except for commercial purpose).

 

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