Effects of E-cigarette on Oral Health – A Systematic Scoping Review


  • M.D.S, Senior Resident, Division of Public Health Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, Delhi – 110029
  • M.D.S, Senior Resident, Division of Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, Delhi – 110029
  • Pro Vice-Chancellor Health Sciences and Professor of Orthodontics, Ramaiah University of Applied Sciences, Bengaluru
  • M.D.S, Associate Professor, Division of Public Health Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, Delhi – 110029
  • M.D.S, Senior Resident, Division of Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, Delhi – 110029
  • M.D.S, Associate Professor, Division of Oral Pathology and Microbiology, Centre for Dental Education and Research, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Delhi – 110029




E-Cigarette, Electronic Nicotine Delivery Systems, Oral Health, Oral Mucosal Lesions, Periodontium, Scoping Review


Background: E-cigarettes have been perceived as a safer product compared to conventional cigarettes and have often been used for the purpose of cigarette smoking cessation. The aim of this scoping review is to provide a systematic review of the existing literature on the effects of e-cigarettes on human oral health and oral tissues. Methodology: Systematic literature search was undertaken and reviewed independently by two experts in online databases till May 2019. Both human and invitro studies were included. Guidelines of preferred reporting items for systematic reviews and meta-analyses for scoping reviews (PRISMA-ScR) were followed for reporting of the data. Results: A total of 24 studies were included following removal of duplicates, title and abstract screening and; full text screening. E-cigarettes have deleterious effects on the oral cavity tissues comprising of clinical findings of periodontium, gingiva, oral hygiene and micro-organism growth. In addition, there is a threat of serious injuries associated with e-cigarette explosion. In-vitro studies reveal e-cigarette use may lead to oxidative damage, altered morphology, reduced cell viability and cytotoxicity of oral epithelial and fibroblast cells. Conclusions: Though e-cigarettes have been found to be less harmful than the conventional cigarette smoking, there is a need to exercise caution while considering it as a smoking cessation tool. Longitudinal population-based studies are required for analyzing its in-vivo effect on oral tissues.


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How to Cite

R, P. R., Kaur, H., Kharbanda, O., Priya, H., Sood, A., & Mishra, D. (2022). Effects of E-cigarette on Oral Health – A Systematic Scoping Review. Journal of Pierre Fauchard Academy (India Section), 36(2), 57–66. https://doi.org/10.18311/jpfa/2022/31264



Systematic Review