Physicochemical and Phytochemical Evaluation of Psoralea corylifolia (Seed) and its Extract

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Authors

  • Arun Kumar
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Vikas Kumar Pal
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Saurabh Singh
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Shivani
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Bimlesh Kumar
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Dileep Singh Baghel
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Kalvatala Sudhakar
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Narendra Kumar Pandey
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Kalpana Thakur
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Sheetu Wadhwa
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Aswin Viswanath
     School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Amrik Singh
     School of Hotel Management and Tourism, Lovely Professional University, Phagwara – 144411, Punjab ,IN
  • Avijit Mazumder
     Department of Pharmacy, NIET, Greater Noida – 201306, Uttar Pradesh ,IN
  • Gurmeet Singh
     Bhaskar Herbaceuticals Pvt. Ltd., Birgunj – 10 ,NP

DOI:

https://doi.org/10.18311/jnr/2024/36242

Keywords:

Pharmacognostic Evaluation, Phytochemical Analysis, Psoriasis

Abstract

Background: Herbal phytochemicals play an important role in the treatment of various dreadful diseases. Psoralea corylifolia is an annual herbaceous plant widely grown in India and other countries Secondary metabolites of P. corylifolia play a crucial role in various skin disorders like psoriasis, eczema and vitiligo as per literary and current reported studies. Various studies have indicated that the seeds of P. corylifolia possess antimicrobial and anti-inflammatory properties. Aim: To evaluate the physicochemical and phytochemical analysis of P. corylifolia. Methods: Psoralen, which is the main active chief constituent present in P. corylifolia, has great therapeutic potential for managing psoriasis. The utilisation of such constituents in Novel Drug Delivery System (NDDS) like micro-emulsions, nano-emulsions, phytosomes, etc. leads to enhanced therapeutic potential. But before proceeding, the formulation development quality control standardisation of every drug is a must for the effective performance of the drug. The standardisation of herbal drugs plays a crucial role in their enhanced therapeutic value. All the standardisation parameters of herbal drugs are widely available in various pharmacopoeias as well as in the Ayurvedic formulary. This article is an attempt to revalidate the physicochemical evaluations of P. corylifolia seeds along with the High-Performance Thin Layer Chromatography (HPTLC) profiling by using potent phytochemical markers. Results: The phytochemical investigation of the extract of P. corylifolia shows the presence of alkaloids, tannins, triterpenoids, glycosides, flavonoids etc. Conclusion: Based on findings, it is concluded that prepared extract can be utilised for further activities like formulation development where the extract can play an important role as compared to simple powder.

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Published

2024-08-31

How to Cite

Kumar, A., Pal, V. K., Singh, S., Shivani, Kumar, B., Baghel, D. S., Sudhakar, K., Pandey, N. K., Thakur, K., Wadhwa, S., Viswanath, A., Singh, A., Mazumder, A., & Singh, G. (2024). Physicochemical and Phytochemical Evaluation of <i>Psoralea corylifolia</i> (Seed) and its Extract. Journal of Natural Remedies, 24(8), 1709–1716. https://doi.org/10.18311/jnr/2024/36242

Issue

Volume 24, Issue 8, August 2024

Section

Research Articles

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Copyright (c) 2024 Arun Kumar, Vikas Kumar Pal, Saurabh Singh, Shivani, Bimlesh Kumar, Dileep Singh Baghel, Kalvatala Sudhakar, Narendra Kumar Pandey, Kalpana Thakur, Sheetu Wadhwa, Aswin Viswanath, Amrik Singh, Avijit Mazumder, Gurmeet Singh (Author)

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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Received 2024-01-16
Accepted 2024-06-25
Published 2024-08-31

 

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