Hypovitaminosis-D, Altered Mineral Status and Electrolytes in Severe Falciparum Malaria
DOI:
https://doi.org/10.21048/ijnd.2020.57.4.25674Keywords:
Vitamin-D, Undernutrition, Malaria, Giemsa Stained Peripheral Blood, Biochemical Tests, Morbidity.Abstract
It is known that malaria and undernutrition are interrelated. The aim is to find out the role of vitamin-D and mineral homeostasis and alteration of electrolytes in severe falciparum malaria. Twenty five patients with uncomplicated falciparum malaria and 60 patients with severe falciparum malaria enrolled in the study. The diagnosis of malaria was made by Giemsa stained peripheral blood smear and rapid diagnostic test. Blood was collected for vitamin-D assay, estimation of calcium, phosphate, magnesium, sodium and potassium along with hematological and biochemical tests. The serum level of vitamin-D (27.8 ± 13.6 ng/ml), calcium (8.8 ± 0.5 mg/dl), phosphate (3.1 ± 0.8 mg/dl), magnesium (1.2 ± 1.8 mg/dl), sodium (133.8 ± 11.4 mEq/L) and potassium (3.1 ± 1.9 mEq/L) were found low among patients with severe malaria. Therefore, the supplement of vitamin-D, minerals and electrolytes may improve mortality and morbidity.Downloads
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Accepted 2020-09-14
Published 2020-11-24
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