Di (2-Ethylhexyl) Phthalate Induced Toxicological Effects on Reproductive System of Female Mice Mus-Musculus

Authors

  • Department of Botany and Biotechnology, Thakur Prasad Singh (T.P.S. College) College, Patliputra University, Patna – 800020, Bihar
  • S. S. Hospital and Research Institute, Patna – 800020, Bihar
  • S. S. Hospital and Research Institute, Patna – 800020, Bihar
  • S. S. Hospital and Research Institute, Patna – 800020, Bihar
  • Department of Botany and Biotechnology, Thakur Prasad Singh (T.P.S. College) College, Patliputra University, Patna – 800020, Bihar

DOI:

https://doi.org/10.18311/jeoh/2019/23333

Keywords:

Corn Oil Reproductive System, DEHP, Hormones, Infertility

Abstract

Di-(2-ethylhexyl) phthalate is an environmental endocrine disruptor and reproductive toxicant. It impairs the structural and functional aspects of female reproduction and also alters the molecular, endocrinological, cytological and biochemical aspects, causing ovarian cycle irregularity and infertility. DEHP was orally administered at lower dose of 10 mg/kg bwt to mice for six to twenty four weeks period which resulted in alterations of the serum levels of hormones estrogen and progesterone. The altered values of hormones were found to be statistically very significant (P<0.001). The present study indicated the adverse effects of exposure of DEHP on female reproductive health.

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References

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Published

2019-09-06

How to Cite

Singh, A., Kumar, R., Singh, J. K., Singh, K. S., & Tanuja. (2019). Di (2-Ethylhexyl) Phthalate Induced Toxicological Effects on Reproductive System of Female Mice <i>Mus-Musculus</i>. Journal of Ecophysiology and Occupational Health, 19(1-2), 71–75. https://doi.org/10.18311/jeoh/2019/23333

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